 Member since Nov '09
Working languages: Spanish to English
Catalan to English
|   David Russell
No nonsense and no delays
Barcelona, Cataluña, Spain Local time: 08:34 CET (GMT+1)
Native in: English  | |
Freelancer,  Verified member | | Translation, Editing/proofreading, Website localization, Software localization | | Specializes in: | | Advertising / Public Relations | Engineering: Industrial | | History | Linguistics | | Medical: Pharmaceuticals | Medical (general) | | Science (general) | Tourism & Travel | | Archaeology |
| Also works in: | | Architecture | Medical: Health Care | | Music | Nutrition | | Real Estate | Religion | | Retail | SAP | | Social Science, Sociology, Ethics, etc. | Manufacturing | | Certificates, Diplomas, Licenses, CVs | Medical: Instruments | | Marketing / Market Research | Business/Commerce (general) | | Medical: Cardiology | Chemistry; Chem Sci/Eng | | Computers: Software | Human Resources | | IT (Information Technology) | Insurance | | International Org/Dev/Coop | Law: Contract(s) | | Management | Genetics |
More Less | Spanish to English - Rates: 0.07 - 0.10 EUR per word / 24 - 35 EUR per hour
Catalan to English - Rates: 0.07 - 0.10 EUR per word / 24 - 35 EUR per hour
| | EUR | | PRO-level points: 312, Questions answered: 172, Questions asked: 214 | Sample translations submitted: 1 | Spanish to English: Example: Medical | Source text - Spanish
Con respecto a la transferencia genética, señaló que, aunque se han superado numerosas dificultades, todavía persisten serias limitaciones, y que entre los diversos sistemas probados hasta la fecha, los mejores son los que emplean vectores virales. Sin embargo, comentó un problema: que los vectores virales eficaces en lo que se refiere a la entrega del ácido nucleico a la célula receptora desencadenan, por otro lado, respuestas inmunológicas que repercuten de forma adversa en la longevidad y magnitud de la expresión del transgén. Este problema es especialmente acusado en el caso de los vectores adenovirales, en los que la activación inmune se manifiesta en forma de un estado inflamatorio intenso. Por el contrario, esta reacción es mínima cuando se emplean vectores retrovirales o de virus adenoasociados (AAV), pero en estos casos la inmunidad preexistente hacia estos vectores compromete tanto la entrega del transgén como la persistencia duradera de las células que lo reciben (células diana). | Translation - English
With regard to gene transfer, he noted that although numerous difficulties have been overcome, there are still serious limitations, and that among the diverse systems tested so far, the best are those that use viral vectors. However, according to the speaker, there is a problem: viral vectors that are effective in delivering nucleic acid to recipient cells also elicit immune responses that adversely effect the longevity and magnitude of transgene expression. This problem is most acute with adenoviral vectors, where immune activation can lead to a severe inflammatory state. By contrast, the reaction is minimal when retroviral or adeno-associated viral (AAV) vectors are used, but in these cases, pre-existing immunity to the vectors compromises both transgene delivery and the long-term persistence of the receiving cells (target cells). |
More Less | | Conveyor belts, Medical | | Master's degree - Institute of Education, University of London | | Years of translation experience: 10. Registered at ProZ.com: Jun 2003. Became a member: Nov 2009. | | N/A | | N/A | | N/A | | Adobe Acrobat, Microsoft Excel, Microsoft Word, Powerpoint, SDL TRADOS | | About me Medical: including pharmaceutical reports, medical reports, articles for journals and conference reports, especially in the fields of cancer and blood disorders, cardiology.
Technical: especially industrial applications.
Business: company literature, auditors reports.
Academic articles: history, social sciences.
Ten years' experience in Barcelona working closely with:
Doctors, hospitals and pharmaceutical companies
Industrial manufacturing companies
Universities
Marketing firms
See examples of my work at:
www.aenor.es
www.sanitas.com
www.canariasonline.com
www.esbelt.com | This user has earned KudoZ points by helping other translators with PRO-level terms. Click point total(s) to see term translations provided.
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Keywords: medical, reports, haemophilia, hemophilia, pharmaceutical, technical, manufacturing, industrial, marketing, history, conveyors, SAP, cardiology, medicina, farmaceuticos, cardiologia, hemofilia, historia, informes médicos, pharmacovigilance, farmacovigilancia, quality, calidad, tourism, turismo, publicidad, advertising.
Profile last updated
Jul 13, 2009 |
The translation workplace 
