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| Working languages: Italian to English English to Italian | aitam NA Local time: 20:45 CET (GMT+1)
Native in: Italian | |
Freelancer, Verified site user | | Translation, Editing/proofreading, Transcription | | Specializes in: | | Medical (general) | Medical: Pharmaceuticals | | Medical: Health Care | Biology (-tech,-chem,micro-) | | Genetics | Science (general) | | Medical: Cardiology | Chemistry; Chem Sci/Eng | | Engineering (general) | | | PRO-level points: 103, Questions answered: 60, Questions asked: 1 | Sample translations submitted: 1 English to Italian: Prophylactic Cranial Irradiation in Extensive Small-Cell Lung Cancer General field: Medical | Source text - English Prophylactic Cranial Irradiation in Extensive Small-Cell Lung Cancer
Background We conducted a randomized trial of prophylactic cranial irradiation in patients with extensive small-cell lung cancer who had had a response to chemotherapy.
Methods Patients between the ages of 18 and 75 years with extensive small-cell lung cancer were randomly assigned to undergo prophylactic cranial irradiation (irradiation group) or receive no further therapy (control group). The primary end point was the time to symptomatic brain metastases. Computed tomography or magnetic resonance imaging of the brain was performed when any predefined key symptom suggestive of brain metastases was present.
Results The two groups (each with 143 patients) were well balanced regarding baseline characteristics. Patients in the irradiation group had a lower risk of symptomatic brain metastases (hazard ratio, 0.27; 95% confidence interval [CI], 0.16 to 0.44; P | Translation - Italian Radioterapia encefalica profilattica in pazienti affetti da carcinoma a piccole cellule - malattia estesa
Background Abbiamo condotto uno studio randomizzato di radioterapia encefalica profilattica in pazienti con carcinoma a piccole cellule – malattia estesa che avessero risposto alla chemioterapia.
Metodi Pazienti di età compresa tra i 18 e i 75 anni con carcinoma a piccole cellule – malattia estesa sono stati randomizzati a ricevere radioterapia encefalica profilattica (gruppo di trattamento) o nessuna ulteriore terapia (gruppo di controllo). L’endpoint primario era il tempo a sviluppo di metastasi cerebrali sintomatiche. Alla comparsa di uno dei sintomi chiave predefiniti suggestivi per malattia encefalica i pazienti venivano sottoposti a tomografia computerizzata o risonanza magnetica cerebrali.
Risultati I due gruppi (ognuno costituito da 143 pazienti) erano ben bilanciati in termini di caratteristiche basali. I pazienti del gruppo di trattamento hanno mostrato un rischio inferiore di sviluppare metastasi encefaliche sintomatiche (hazard ratio, 0,27; intervallo di confidenza [CI] al 95%, 0,16 – 0,44; P | More Less | | Medical_MA | | Years of translation experience: 3. Registered at ProZ.com: May 2009. | | N/A | English to Italian (Brazil: Medcenter Portal) English to Italian (Italy: Nexilab) | | N/A | | Adobe Acrobat, Microsoft Excel, Microsoft Word, Powerpoint | | Keywords: Medical (general, oncology, cardiology, immunology, hematology, surgery), biology, chemistry, pharmaceuticals, clinical studies, health care management
Profile last updated Jan 22, 2010 |