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| Working languages: Spanish to English English to Spanish | | Ruben de Regil Chemical and Biotechnolgical Sciences NA Local time: 22:36 CET (GMT+1)
Native in: Spanish | |  | Willingness to Work Again No feedback collected |
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| Freelancer | | Translation, Editing/proofreading, Transcription, Project management | | Specializes in: | | Management | Chemistry; Chem Sci/Eng | | Biology (-tech,-chem,micro-) | Genetics | | Medical: Pharmaceuticals | Energy / Power Generation | | Manufacturing |
| Also works in: | | Biology (-tech,-chem,micro-) | Business/Commerce (general) | | Engineering (general) | Certificates, Diplomas, Licenses, CVs | | Food & Dairy | Petroleum Eng/Sci | | Tourism & Travel |
More Less | Spanish to English - Rates: 0.05 - 0.06 ARS per word / 25 - 25 ARS per hour English to Spanish - Rates: 0.05 - 0.06 ARS per word / 25 - 25 ARS per hour | | Questions answered: 10, Questions asked: 22 Easy / 25 PRO, PRO-level points: 12 | | 0 entries | Sample translations submitted: 2English to Spanish: Síntesis of trans-6-fenoxiacetamido-1-metilen-3,3-dicarboximetil-1-carbapenam General field: Science Detailed field: Chemistry; Chem Sci/Eng | Source text - English A similar procedure is described by Schmidt and
Poise1 (6) for the preparation of racemic proline.
The pyrrolidine 2a was obtained in five steps from
4-hydroxy-L-proline 3a.2 In order to obtain a
1-methylene-1-carbapenam with the same configuration
at C2 as in penicillins, 4-hydroxy-Dproline
should be used as a starting material.
However, in these experiments the more readily
available L-enantiomer was used. Oxidation of
N-tert-Boc-4-hydroxy-L-proline 3b with Cr0,lpyridine
in CH,Cl, gave the ketone 3c (60%), which
was converted into the N-protected 4-methylenepyrrolidine
3d by condensation with methylenetriphenylphosphorane
(4 equiv.) in THF (80% yield). | Translation - Spanish Un procedimiento similar esta descrito por Schmidt y Poise (6) para la preparacion de prolina racémica. La pirrolidona 2a se obtuvo en 5 pasos a partir de la 4-hidroxi-L-prolina 3a. Para obtener 1-metilen-1-carbapenam con la misma configuracion en C2 como en las penicilinas, se debe emplear 4-hidroxi-D-prolina como sustancia de partida. Sin embargo, en estos experimentos se uso el enantiómero L por su fácil disponibilidad. La oxidación de N-tert-Boc-4-hidroxi-L-proline 3b con CrO3/piridina en CH2Cl, dio como resultado la cetona 3c (60%), la cual fue convertida en la 4-metilenpirrolidine protegida en el N 3d mediante condensación con metilentrifenilfosforane (4 equiv.) en THF (80% de rend.) | Spanish to English: The role of enzyme dynamics and tunnelling in catalysing hydride transfer General field: Science Detailed field: Chemistry; Chem Sci/Eng | Source text - Spanish R [4-2H]-NADPH se preparó mediante una reducción estereoespecífica de NADP con 2-propanol-d8 (más del 99.7% D en 2C de acuerdo a la determinación por 1H-RMN) usando una alcohol-deshidrogenasa de Thermoanaerobium brockii (tbADH). Se sintetizó R [4-3H]-NADPH (680 mCi/mmol) mediante la reducción de NADP con glucosa-[1-3H] usando una glucosa deshidrogenasa (GluDH) de Cryptococcus uniguttulatus, seguida de una oxidación del NADPH resultante con acetona usando tbADH y posteriormente una segunda reducción con glucosa no marcada usando GluDH como se describe en mayor detalle en otras publicaciones. Se preparó [Ad-14C]-NADPH (50 mCi/mmol) mediante la fosrolilación en 2´ de [Ad-14C]-nicotinamida adenina dinucleótido (NAD ) usando una NAD kinasa de hígado de pollo para producir [Ad-14C]-NADP , seguida de una reducción con glucosa usando GluDH tal como se describe en otras publicaciones. | Translation - English R [4-2H]-NADPH was prepared through stereospecific reduction of NADP with 2-propanol-d8 (greater than 99.7% D at 2C as determined by 1H-NMR) using alcohol dehydrogenase from Thermoanaerobium brockii (TbADH). R [4-3H]-NADPH (680 mCi/mmol) was synthesized by reduction of NADP with [1-3H]-glucose using glucose dehydrogenase (GluDH) from Cryptococcus uniguttulatus, followed by oxidation of the resulting NADPH with acetone using tbADH and then a second reduction with unlabelled glucose using GluDH as described in more detail elsewhere.
[Ad-14C]-NADPH (50 mCi mmolK1) was prepared by 2´-phosphorylation of [Ad-14C]-nicotinamide adenine dinucleotide (NADC) using an NADC kinase from chicken liver to produce [Ad-14C]-NADP , followed by reduction with
glucose using GluDH as described elsewhere. |
More Less | | Law | | Years of translation experience: 5. Registered at ProZ.com: May 2003. | | N/A | | N/A | | N/A | | Adobe Acrobat, MS Office, SDL TRADOS, Wordfast | | http://www.bosiet.com | | Ruben de Regil endorses ProZ.com's Professional Guidelines. | | About me
Ruben de Regil
I am a scientist in chemical sciences and recently resuming again my work as a freelancer translator for jobs in the fields of Biotechnology, Chemistry, Biochemistry, Chemical Engineering, Molecular Biology and Microbiology.
EDUCATION
2009 PhD in Sustainable Chemistry
2005 MSc Biochemical Sciences
2001 Freelance translator.
1997 BSc Chemical Engineering
WORK EXPERIENCE
Jan/2001-Dec/2002 Agency Translator
Feb/2003 SP>EN Busines Law Project for DuPont de Mexico
Mar/2003 SP>EN Busines Law Project for Fibra DuPont Colombia
Jun/2003 SP>EN Busines Law Project for Nylon de Mexico
Jun/2003 SP>EN Busines Law Project for Nylmex S.A. de C.V.
Ago/2003 SP>EN Busines Law Project for Polykron S.A. de C.V.
Sep/2003 SP>EN Busines Law Project for UNIMOR S.A. de C.V.
| This user has earned KudoZ points by helping other translators with PRO-level terms. Click point total(s) to see term translations provided.
Total pts earned: 19 PRO-level pts: 12
| | Top languages (PRO) | | English to Spanish | 8 | | Spanish to English | 4 | | Top general fields (PRO) | | Science | 4 | | Bus/Financial | 4 | | Tech/Engineering | 4 | | Top specific fields (PRO) | | Chemistry; Chem Sci/Eng | 4 | See all points earned > |
| Keywords: business, corporate, letter, proofreading, engineering, chemical, science, biotechnology, biochemsitry, molecular biology, chemistry, microbiology
Profile last updated Jul 20 |