指令成分

English translation: transmitters / signaling molecules

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Japanese term or phrase:指令成分
English translation:transmitters / signaling molecules
Entered by: Shannon Morales

18:44 Jun 7, 2008
Japanese to English translations [PRO]
Medical - Cosmetics, Beauty / Skin
Japanese term or phrase: 指令成分
Secreted within the skin -- examples given include a-MSH and TNF. I understand the meaning, but what is the proper English term for these? Thank you!
Shannon Morales
United States
Local time: 09:07
α-melanocyte stimulating hormone (α-MSH), Tumor necrosis factor-alpha (TNF-alpha)
Explanation:
Transmitter Substance (constituent)

α-melanocyte stimulating hormone (α-MSH)

http://www.co-pulmonarymedicine.com/pt/re/copulmonary/abstra...
00002.htm;jsessionid=LLgNy3yL7VDGBGjRJzMLn6DKvPcjnv2yjyfh3yfnxQzb5LGjsYTz!1593807172!181195629!8091!-1


Tumor necrosis factor-alpha (TNF-alpha)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=19...

http://content.karger.com/produktedb/produkte.asp?doi=10.115...

(TNF – Tumor Not Found?????)


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Note added at 5 hrs (2008-06-08 00:21:04 GMT)
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Sorry. Please try this one.
http://en.wikipedia.org/wiki/Melanocyte-stimulating_hormone

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Note added at 14 hrs (2008-06-08 09:40:32 GMT)
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Sorry Again, I didn't read your question well. You know the meaning of a-MSH and TNF.

--------------------------------------------------
Note added at 1 day2 hrs (2008-06-08 20:56:35 GMT)
--------------------------------------------------

Hi,

a-MSH is melanotropinα-Melanocyte Stimulating *Hormone.
According to the below link;

<<Hormone>>

http://en.wikipedia.org/wiki/Hormone

Hormones are chemicals released by cells that affect cells in other parts of the body. Only a small amount of hormone is required to alter cell metabolism.It is also a chemical messenger that transports a signal from one cell to another.

<<Neurotransmitter>>

http://en.wikipedia.org/wiki/Neurotransmitter

Neurotransmitters are chemicals that are used to relay, amplify and modulate signals between a neuron and another cell.[1] According to the prevailing beliefs of the 1960s, a chemical can be classified as a neurotransmitter if it meets the following conditions:
There are precursors and/or synthesis enzymes located in the presynaptic side of the synapse;
The chemical is present in the presynaptic element
It is available in sufficient quantity in the presynaptic neuron to affect the postsynaptic neuron;
There are postsynaptic receptors and the chemical is able to bind to them

So they are two different things.

But Japanese wiki says that ホルモン(英:hormone)とは、動物の体内において、ある決まった器官で合成・分泌され、体液(血液)を通して体内を循環し、別の決まった器官でその効果を発揮する生理活性物質のこと。生体内の特定の器官の働きを調節するための情報伝達を担う物質であり、栄養分などとは違って、ホルモンの体液中の濃度は非常に微量であるのが特徴。

It is not Neurotransmitters, but I also thought that it is a kind of “transmitter”.

transmitters (a-MSH, AgRP and 5-HT) modify the electrical activity of identified hypothalamic. neurons. Using electrophysiological, biochemical and ...

http://www.blackwell-synergy.com/doi/abs/10.1111/j.1749-6632...

But it is a very good idea to wait for another suggestions.

Good Luck!


--------------------------------------------------
Note added at 1 day2 hrs (2008-06-08 21:09:07 GMT)
--------------------------------------------------

Sorry for my typo.
It is not a Neurotransmitter,

--------------------------------------------------
Note added at 1 day3 hrs (2008-06-08 22:04:11 GMT)
--------------------------------------------------

This might help you understand messenger and transmitter.
http://www.psychiatrictimes.com/display/article/10168/114763...

--------------------------------------------------
Note added at 1 day4 hrs (2008-06-08 23:03:21 GMT)
--------------------------------------------------


**Signal transduction**
In biology, signal transduction refers to any process by which a cell converts one kind of signal or stimulus into another.

http://en.wikipedia.org/wiki/Signal_transduction

**a molecular transmitter (hormone or factor)**

https://www.msu.edu/course/lbs/149h/Cell Signal.html

Selected response from:

sumire (X)
United States
Grading comment
Thank you so much for all your research on this! It seems there's no fixed term for it, but from the links you provided, it appears that both "signaling molecules" and "transmitters" cover both substances, so I'll use one of those. Otsukaresama deshita!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1active ingredients
Ruth Sato
2α-melanocyte stimulating hormone (α-MSH), Tumor necrosis factor-alpha (TNF-alpha)
sumire (X)
1stimulating agent
Krzysztof Łesyk


Discussion entries: 1





  

Answers


16 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
active ingredients


Explanation:
My suggestion is based on 指令 having the meaning of "official/oder/prescript" and 成分 taking the meaning of "ingredients/or components". If we look at the instructions on make up or medicine, there is usually a section of "active ingredients", so I was thinking that it might fit here. What do you think?

Ruth Sato
United States
Local time: 10:07
Native speaker of: English

Peer comments on this answer (and responses from the answerer)
agree  sumire (X): Maybe
1 hr
  -> Thanks--I wasn't certain either (^_-)
Login to enter a peer comment (or grade)

5 hrs   confidence: Answerer confidence 2/5Answerer confidence 2/5
α-melanocyte stimulating hormone (α-MSH), Tumor necrosis factor-alpha (TNF-alpha)


Explanation:
Transmitter Substance (constituent)

α-melanocyte stimulating hormone (α-MSH)

http://www.co-pulmonarymedicine.com/pt/re/copulmonary/abstra...
00002.htm;jsessionid=LLgNy3yL7VDGBGjRJzMLn6DKvPcjnv2yjyfh3yfnxQzb5LGjsYTz!1593807172!181195629!8091!-1


Tumor necrosis factor-alpha (TNF-alpha)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=19...

http://content.karger.com/produktedb/produkte.asp?doi=10.115...

(TNF – Tumor Not Found?????)


--------------------------------------------------
Note added at 5 hrs (2008-06-08 00:21:04 GMT)
--------------------------------------------------

Sorry. Please try this one.
http://en.wikipedia.org/wiki/Melanocyte-stimulating_hormone

--------------------------------------------------
Note added at 14 hrs (2008-06-08 09:40:32 GMT)
--------------------------------------------------

Sorry Again, I didn't read your question well. You know the meaning of a-MSH and TNF.

--------------------------------------------------
Note added at 1 day2 hrs (2008-06-08 20:56:35 GMT)
--------------------------------------------------

Hi,

a-MSH is melanotropinα-Melanocyte Stimulating *Hormone.
According to the below link;

<<Hormone>>

http://en.wikipedia.org/wiki/Hormone

Hormones are chemicals released by cells that affect cells in other parts of the body. Only a small amount of hormone is required to alter cell metabolism.It is also a chemical messenger that transports a signal from one cell to another.

<<Neurotransmitter>>

http://en.wikipedia.org/wiki/Neurotransmitter

Neurotransmitters are chemicals that are used to relay, amplify and modulate signals between a neuron and another cell.[1] According to the prevailing beliefs of the 1960s, a chemical can be classified as a neurotransmitter if it meets the following conditions:
There are precursors and/or synthesis enzymes located in the presynaptic side of the synapse;
The chemical is present in the presynaptic element
It is available in sufficient quantity in the presynaptic neuron to affect the postsynaptic neuron;
There are postsynaptic receptors and the chemical is able to bind to them

So they are two different things.

But Japanese wiki says that ホルモン(英:hormone)とは、動物の体内において、ある決まった器官で合成・分泌され、体液(血液)を通して体内を循環し、別の決まった器官でその効果を発揮する生理活性物質のこと。生体内の特定の器官の働きを調節するための情報伝達を担う物質であり、栄養分などとは違って、ホルモンの体液中の濃度は非常に微量であるのが特徴。

It is not Neurotransmitters, but I also thought that it is a kind of “transmitter”.

transmitters (a-MSH, AgRP and 5-HT) modify the electrical activity of identified hypothalamic. neurons. Using electrophysiological, biochemical and ...

http://www.blackwell-synergy.com/doi/abs/10.1111/j.1749-6632...

But it is a very good idea to wait for another suggestions.

Good Luck!


--------------------------------------------------
Note added at 1 day2 hrs (2008-06-08 21:09:07 GMT)
--------------------------------------------------

Sorry for my typo.
It is not a Neurotransmitter,

--------------------------------------------------
Note added at 1 day3 hrs (2008-06-08 22:04:11 GMT)
--------------------------------------------------

This might help you understand messenger and transmitter.
http://www.psychiatrictimes.com/display/article/10168/114763...

--------------------------------------------------
Note added at 1 day4 hrs (2008-06-08 23:03:21 GMT)
--------------------------------------------------


**Signal transduction**
In biology, signal transduction refers to any process by which a cell converts one kind of signal or stimulus into another.

http://en.wikipedia.org/wiki/Signal_transduction

**a molecular transmitter (hormone or factor)**

https://www.msu.edu/course/lbs/149h/Cell Signal.html



sumire (X)
United States
Works in field
Native speaker of: Native in JapaneseJapanese
PRO pts in category: 8
Grading comment
Thank you so much for all your research on this! It seems there's no fixed term for it, but from the links you provided, it appears that both "signaling molecules" and "transmitters" cover both substances, so I'll use one of those. Otsukaresama deshita!
Login to enter a peer comment (or grade)

1 day 11 hrs   confidence: Answerer confidence 1/5Answerer confidence 1/5
stimulating agent


Explanation:
Far from any field I work in, but biology used to be my big hobby, so here's a (hopefully) educated guess. Of course that wholly depends on what exactly it is that the substance is doing, but both α-MSH and TNF-alpha seem to be stimulating something, hence my answer.

Maybe you could even use "catalyst", but that might be misinterpreted as a chemical (e.g. reaction catalyst) rather than biological (e.g. cell growth catalyst) term.

Krzysztof Łesyk
Japan
Local time: 23:07
Native speaker of: Native in PolishPolish
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