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ligand protein

Spanish translation: proteína ligando

10:17 Nov 6, 2018
English to Spanish translations [PRO]
Law/Patents - Patents / ligand protein
English term or phrase: ligand protein
In some preferred embodiments, the disclosure features BFP3 format bispecific fusion proteins including one or more N-terminus antigen binding subunits, a central Fc polypeptide core, and one or more C-terminus ligand proteins.
In one embodiment, the one or more N-terminus antigen binding subunits (BD2) can be anti-PD-1 and/or anti-PD-1L antigen binding subunits, the central Fc polypeptide core can be an IgG1 or IgG4 Fc region polypeptide (CH2 and CH3), and the one or more C-terminus ligand proteins (BD1) can include, for example, GITRL, OX40L, CD40L, TNF-α, and/or CD137.

No me queda claro si es proteína ligando directamente.

https://es.wikipedia.org/wiki/Acoplamiento_molecular

MUCHAS GRACIAS
Romina Zaleski
Local time: 17:29
Spanish translation:proteína ligando
Explanation:
Es como se conoce.
Selected response from:

Maria Iglesia Ramos
Spain
Grading comment
Selected automatically based on peer agreement.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +3proteína ligando
Maria Iglesia Ramos
3proteína ligante
maría bergós
3dominio [proteína] de unión a ligando C-terminal
Chema Nieto Castañón
3proteína ligando
Clara Bugallo


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
proteína ligando


Explanation:
Es como se conoce.

Maria Iglesia Ramos
Spain
Works in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 4
Grading comment
Selected automatically based on peer agreement.

Peer comments on this answer (and responses from the answerer)
agree  Walter Landesman
1 hr
  -> Thank you Walter
agree  Yaotl Altan
7 hrs
agree  Carlos Teran: Bioquímica en su mas alto nivel ;)
12 hrs
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1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5
proteína ligante


Explanation:
.


    https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000300017
    Reference: http://biomodel.uah.es/metab/expresion/TBP.htm
maría bergós
Uruguay
Native speaker of: Native in SpanishSpanish
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3 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
C-terminus ligand protein
dominio [proteína] de unión a ligando C-terminal


Explanation:
En este caso diría se alude a un dominio [dominio proteico; a una proteína en sí misma] de unión a ligando C-terminal.
Por ejemplo,

MR tienen tres grandes dominios funcionales: un dominio N-terminal (NTD), seguido por un dominio de unión al ADN central (DBD), y un dominio de unión a ligando C-terminal (LBD),...
https://www.google.es/url?sa=t&source=web&rct=j&url=https://...

Así, tiene sentido en tu original,
fusion proteins including one or more N-terminus antigen binding subunits, a central Fc polypeptide core, and one or more C-terminus ligand proteins.
... Así como la continuación, aludiendo a las distintas subunidades;
(...) the central Fc polypeptide core can be an IgG1 or IgG4 Fc region polypeptide (CH2 and CH3), and the one or more C-terminus ligand proteins (BD1) can include, for example, GITRL,...


Chema Nieto Castañón
Spain
Local time: 22:29
Native speaker of: Native in SpanishSpanish
PRO pts in category: 4
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5 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
proteína ligando


Explanation:
Justamente estoy haciendo una traducción donde me apareció la palabra "ligand" para traducir y en el diccionario de medicina me dice que es una molécula.

Clara Bugallo
Argentina
Local time: 17:29
Native speaker of: Native in SpanishSpanish
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