self-looping

Russian translation: с самоформирующейся петлей

09:07 Nov 27, 2018
English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: self-looping
AONs are characterized by a sequence that is complementary to a target RNA sequence and by the presence of a stem-loop structure , which is preferably non-complementary to the target RNA.
Such oligonucleotides are referred to as ‘self-looping AONs’
oksz
Ukraine
Local time: 22:39
Russian translation:с самоформирующейся петлей
Explanation:
https://patents.google.com/patent/WO2017220751A1/en
Another important aspect of the AON of the present invention is that it does not have a portion that is complementary to the target RNA or the RNA region that comprises the target adenosine that allows the AON in itself to fold into an intramolecular hairpin or other type of (stem-) loop structure (herein also referred to as "auto-looping" or "self-looping"), and which may potentially act as a structure that sequesters ADAR.
https://patents.google.com/patent/RU2432165C2/ru
Шпилечная интерферирующая РНК представляет собой отдельную молекулу (например, отдельная олигонуклеотидая цепь), содержащую и смысловую и антисмысловую цепи интерферирующей РНК в виде структуры стебля-петли или шпильки (например, кшРНК). ...
Полученный в результате транскрипт РНК складывается сам с собой с формированием структуры стебля-петли.
Selected response from:

hawkwind
Russian Federation
Local time: 05:39
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1с самоформирующейся петлей
hawkwind
3образующий петлю
Igor Andreev


  

Answers


2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
с самоформирующейся петлей


Explanation:
https://patents.google.com/patent/WO2017220751A1/en
Another important aspect of the AON of the present invention is that it does not have a portion that is complementary to the target RNA or the RNA region that comprises the target adenosine that allows the AON in itself to fold into an intramolecular hairpin or other type of (stem-) loop structure (herein also referred to as "auto-looping" or "self-looping"), and which may potentially act as a structure that sequesters ADAR.
https://patents.google.com/patent/RU2432165C2/ru
Шпилечная интерферирующая РНК представляет собой отдельную молекулу (например, отдельная олигонуклеотидая цепь), содержащую и смысловую и антисмысловую цепи интерферирующей РНК в виде структуры стебля-петли или шпильки (например, кшРНК). ...
Полученный в результате транскрипт РНК складывается сам с собой с формированием структуры стебля-петли.

hawkwind
Russian Federation
Local time: 05:39
Native speaker of: Native in RussianRussian
PRO pts in category: 112

Peer comments on this answer (and responses from the answerer)
agree  Vladyslav Golovaty
8 hrs
  -> Спасибо!
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4 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
образующий петлю


Explanation:
антисмысловой олигонуклеотид, образующий петлю
как вариант

Igor Andreev
Local time: 22:39
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 1427
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