14:31 Oct 28, 2019 |
English to Spanish translations [PRO] Medical - Mathematics & Statistics / Clinical trials | |||||||
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| Selected response from: Juan Arturo Blackmore Zerón Mexico Local time: 08:55 | ||||||
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Summary of answers provided | ||||
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3 | pruebas estadísticas completas |
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2 | ensayos de poder estadistico total |
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3 -1 | pruebas plenamente validas |
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Summary of reference entries provided | |||
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Refs. |
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Discussion entries: 4 | |
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ensayos de poder estadistico total Explanation: https://www.elsevier.es/es-revista-revista-medica-clinica-la... "El complemento 1- β representa la probabilidad de observar en la muestra una determinada diferencia o efecto y es a lo que se llama el poder estadístico o potencia del estudio." I'm not sure how "fully" would be expressed in Spanish. I know that it is reported as a %, for example: https://www.fisterra.com/mbe/investiga/poder_estadistico/pod... "Cálculo del poder estadístico de un estudio Así, puede concluirse que de haber estudiado 130 pacientes por grupo, se obtiene una potencia de sólo el 36.6% para detectar una diferencia mínima del 10%, una potencia del 68% para detectar una diferencia del 15% y de un 90.2% para una diferencia del 20%. Este tipo de gráficos resulta muy útil tanto en la fase de diseño de un estudio como a la hora de valorar a posteriori el poder de una investigación. So maybe "ensayos de 100% poder estadistico / potencia estadistica" |
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pruebas estadísticas completas Explanation: "Determining the optimal sample size for a study assures an adequate power to detect statistical significance. Hence, it is a critical step in the design of a planned research protocol. Using too many participants in a study is expensive and exposes more number of subjects to procedure. Similarly, if study is underpowered, it will be statistically inconclusive and may make the whole protocol a failure. This paper covers the essentials in calculating power and sample size for a variety of applied study designs. Sample size computation for single group mean, survey type of studies, 2 group studies based on means and proportions or rates, correlation studies and for case-control for assessing the categorical outcome are presented in detail." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409926/ "Based on these factors, the study must have an adequate sample size, relative to the goals and the possible variabilities of the study. Sample must be ‘big enough’ such that the effect of expected magnitude of scientific significance, to be also statistically significant. Same time, It is important that the study sample should not be ‘too big’ where an effect of little scientific importance is nevertheless statistically detectable. In addition, sample size is important for economic reasons: An under-sized study can be a waste of resources since it may not produce useful results while an over-sized study uses more resources than necessary. In an experiment involving human or animal subjects, sample size is a critical ethical issue. Since an ill-designed experiment exposes the subjects to potentially harmful treatments without advancing knowledge." these were three fully powered studies with more than xx patients each: estos fueron tres estudios estadísticos completos con mas de xx pacientes en cada uno |
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pruebas plenamente validas Explanation: https://expansion.mx/expansion/2011/09/14/xes-el-que-buscan |
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13 mins |
Reference: Refs. Reference information: HIV Integrase inhibitors - ASX www.asx.com.au › asxpdf › pdf Nov 24, 2014 - Three separate **fully powered clinical studies** discussed at the 20th International AIDS Conference in Melbourne. • Compared treatment based ... Clinical Trial: Early Psychological Intervention to Prevent ... https://trials.trialscout.com › clinical-trial-details › early-psychological-inter... Descriptive statistics will be used to understand the feasibility of testing the written exposure therapy intervention as part of a larger, **fully powered clinical trial.** Sample sizes in CTs: truth seeking - CEBM https://www.cebm.net › truth-seeking-sample-sizes-in-clinical-trials Sep 21, 2018 - “The average power of a clinical trial is only 9%, according to a recent ... asking a funder to commit to the huge cost of a fully-powered trial. On participatory research and building the evidence base ... https://dart.ed.ac.uk › Blog › Autism Oct 8, 2018 - The project is a multi-site fully-powered clinical trial of a new manualised .... **It's built on a theoretical model and broad range of evidence that ...** -------------------------------------------------- Note added at 15 mins (2019-10-28 14:46:48 GMT) -------------------------------------------------- Enfermedades Raras - Cursos de Enfermería www.isfie.org › documentos › er-retos-y-oportunidades-libro desafío de diseñar un ensayo clínico para una enfermedad tan rara. El desarrollo de ...... ****denominados estudios de gran potencia. *** Tradicionalmente, los ... |
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