This question was closed without grading. Reason: Other
Mar 4, 2011 18:34
13 yrs ago
Chinese term

重要靶标

Chinese to English Other Medical: Pharmaceuticals
the whole sentence is "经计算机虚拟筛选,发现系列新奇结构的三萜化合物与多个神经退行性疾病相关的重要靶标结合,如beta-分泌酶等" I don't understand is this phrase mean those triterpenoid compounds can cure the neurodegenerative disease or means they have similar chemical structures or something else? :S

Proposed translations

5 hrs

important targets

important targets

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Note added at 5 hrs (2011-03-05 00:21:36 GMT)
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意思是说,该化合物能与一些作用靶标结合,而这些靶标是与神经退行性疾病相关的,从而该化合物通过这些作用靶标而可能治疗神经退行性疾病。
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36 days

crucial targets

in English paper, crucial targets refer to the target that are very important and key in life activities.
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72 days

key targets

The word key not only means important but also evokes the image of opening a lock, similar to solving a problem. Neurodegenerative diseases are the problem discussed in the paragraph.

Beta-secretase enzyme is important in secretion of beta-amyloid, the components that form plague lesion in patients of Alzheimer's disease. Thus if some compound can bind to this enzyme (and perhaps inhibit its activity), one hopes that symptoms of the neurodegenerative diseases can be ameliorated or the diseases can be cured. Thus, problem solved.
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