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AH van 98 msec, HV van 45 msec

English translation: AH interval= 98 msec; HV interval= 45 msec

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17:32 Dec 26, 2003
Dutch to English translations [PRO]
Medical
Dutch term or phrase: AH van 98 msec, HV van 45 msec
IN basal circumstances the conductivity intervals are normal (AH of 98 msec, HV of 45 msec).
Andre de Vries
United Kingdom
Local time: 09:31
English translation:AH interval= 98 msec; HV interval= 45 msec
Explanation:
The AH interval is the time period in which the cardiac electric impulse travels between the sinus node and the His bundle. The HV interval is the period of time during which the impulse travles between the His bundle and the ventricles.

Good luck

Elena

BACKGROUND: CVT-510, N-(3(R)-tetrahydrofuranyl)-6-aminopurine riboside, is a selective A(1)-adenosine receptor agonist with potential potent antiarrhythmic effects in tachycardias involving the atrioventricular (AV) node. This study, the first in humans, was designed to determine the effects of CVT-510 on AV nodal conduction and hemodynamics. METHODS AND RESULTS: Patients in sinus rhythm with normal AV nodal function at electrophysiologic study (n = 32) received a single intravenous bolus of CVT-510. **AH and HV intervals** were measured during sinus rhythm and during atrial pacing at 1, 5, 10, 15, 20, 30, 45, and 60 minutes after the bolus. Increasing doses of CVT-510 (0.3 to 10 microg/kg) caused a dose-dependent increase in the **AH interval**....



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xxxElena Sgarbo
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Thanks again for your great help today.
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Summary of answers provided
5 +1AH interval= 98 msec; HV interval= 45 msecxxxElena Sgarbo


  

Answers


24 mins   confidence: Answerer confidence 5/5 peer agreement (net): +1
AH interval= 98 msec; HV interval= 45 msec


Explanation:
The AH interval is the time period in which the cardiac electric impulse travels between the sinus node and the His bundle. The HV interval is the period of time during which the impulse travles between the His bundle and the ventricles.

Good luck

Elena

BACKGROUND: CVT-510, N-(3(R)-tetrahydrofuranyl)-6-aminopurine riboside, is a selective A(1)-adenosine receptor agonist with potential potent antiarrhythmic effects in tachycardias involving the atrioventricular (AV) node. This study, the first in humans, was designed to determine the effects of CVT-510 on AV nodal conduction and hemodynamics. METHODS AND RESULTS: Patients in sinus rhythm with normal AV nodal function at electrophysiologic study (n = 32) received a single intravenous bolus of CVT-510. **AH and HV intervals** were measured during sinus rhythm and during atrial pacing at 1, 5, 10, 15, 20, 30, 45, and 60 minutes after the bolus. Increasing doses of CVT-510 (0.3 to 10 microg/kg) caused a dose-dependent increase in the **AH interval**....






    Reference: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d...
xxxElena Sgarbo
Native speaker of: Native in SpanishSpanish
PRO pts in pair: 12
Grading comment
Thanks again for your great help today.

Peer comments on this answer (and responses from the answerer)
agree  writeaway: good thing you're on call this afternoon! :-)
42 mins
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