co-crystals

For term searches and specialty glossaries, please try the new GBK glossaries
00:54 Sep 4, 2020
English to Croatian translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
Glossary-building KudoZ




Question posted on behalf of translation team:
GBK medical and pharma specialists


This question will remain open until an answer receives the required level of agreement from peers. Submission is still possible.


Summary of translations provided
4 +1kokristali
Kate Perak


  

Translations offered


9 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
kokristali


Definition from Repozitorij ZIR:
Oblici višekomponentnih supramolekulskih sustava građeni od nenabijenih farmakološki aktivnih molekula i farmakološki prihvatljivih molekula sučinitelja (koformera), koji su u kristalu povezani međumolekulskim privlačnim silama poput vodikovih i halogenskih veza, Keesomovih i Londonovih sila itd.
Kokristalizacija je korisna u farmaceutskoj industriji jer omogućava promjenu fizikalno-kemijskih svojstava farmakološki aktivnih tvari bez mijenjanja njihove molekulske strukture.

Example sentence(s):
  • Kokristali s antranilnom i benzojevom kiselinom dosad nisu bili poznati u literaturi i okarakterizirani su uz pomoć difrakcije rendgenskih zraka na praškastim uzorcima i uz pomoć Ramanove spektroskopije. - CROSBI  
  • Kako bi se izučila mogućnost priprave supramolekulskih arhitektura temeljem halogenske veze Co-Cl···I u kokristalima koji sadrže metaloorganske jedinke CoCl2L2 i perhalogenirane spojeve, istraživanje doktorandice Lisac uključuje organsku, metaloorgansku i supramolekulsku sintezu te termalnu, spektroskopsku i strukturnu analizu materijala metodom difrakcije rentgenskih zraka. - HRZZ  
  • Soli, solvati i kokristali pripadaju u višekomponentne molekulske kristale, a razlikuju se po vrsti molekula od kojih se kristal sastoji. Kokristali i solvati se uvijek sastoje od nenabijenih molekula, dok se soli sastoje od nabijenih. Prema strogoj definiciji glavna razlika između solvata i kokristala je ta što je barem jedna komponenta koja ulazi u sastav solvata pri sobnoj temperaturi tekućina (odnosno otapalo), dok su kod kokristala sve komponente koje ulaze u njegov sastav pri sobnoj temperaturi čvrste tvari. - PMF  
Kate Perak
Croatia
Local time: 06:26
Native speaker of: Native in CroatianCroatian
PRO pts in category: 60

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Mirna Vilisic
64 days
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.


See also:

Your current localization setting

English

Select a language

Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search