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00:55 Sep 4, 2020
English to Dutch translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
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12 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5

Definition from own experience or research:
Seems pretty straightforward to translate this as cokristallen. A lot of hits on Google for this in Dutch.

Example sentence(s):
  • Cokristallen zijn "kristallijne vaste stoffen die enkelfasig elementen met twee of meer verschillende moleculaire of ionische verbindingen in het algemeen in een stoichiometrische verhouding, die niet solvaten of eenvoudige zouten zijn." Een ruimere definitie is dat cokristallen "bestaan uit twee of meer componenten die een unieke kristalstructuur hebben unieke eigenschappen." Verschillende subclassificaties van cokristallen bestaan. - Wikipedia  
United States
Local time: 13:29
Native speaker of: Native in FlemishFlemish, Native in DutchDutch, Native in EnglishEnglish
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