copy-up

German translation: hyperaktiv

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:copy-up
German translation:hyperaktiv
Entered by: Ingo Dierkschnieder

08:43 Jun 6, 2006
English to German translations [PRO]
Science - Genetics / plasmid production
English term or phrase: copy-up
Aus einem Patent zur gentechnischen Manipulation von Plasmiden:

"The replication origin for pVC0396 is derived from plasmid pMM1, a temperature-sensitive *copy-up* mutant derived from ColE1. pMM1 has a low copy number when maintained at 30°C, but it is amplified to high copy number when maintained at or above 37°C."

Der Ausdruck kommt im Text leider nur dieses eine Mal vor, meine schlauen Bücher schweigen sich dazu aus und eine Internetsuche hat mir auch nicht weitergeholfen. Kann sich jemand darunter etwas vorstellen?

Vielen Dank im Voraus.
Ingo Dierkschnieder
United Kingdom
Local time: 18:45
hyperaktiv
Explanation:
Eine Suche nach "copy-up mutant" bringt unter anderem folgende Ergebnisse:

"Certain hyperactive ("copy-up") mutants of p can activate the g
origin more efficiently than the equivalent amount of wild-type
(wt) p."

http://jb.asm.org/cgi/reprint/177/23/6732.pdf


"...we used copy-up p mutants. These mutants contain single
amino acid substitutions and increase the copy number of core
plasmids two- to fourfold relative to the copy number at the
same level of wt p (60)."

http://jb.asm.org/cgi/reprint/177/22/6338.pdf
Selected response from:

Oliver Annacker
Sweden
Local time: 19:45
Grading comment
Vielen Dank, auch wenn ich nicht restlos überzeugt bin, dass hyperaktive Mutanten gemeint sind.
4 KudoZ points were awarded for this answer



Summary of answers provided
3hyperaktiv
Oliver Annacker


  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5
hyperaktiv


Explanation:
Eine Suche nach "copy-up mutant" bringt unter anderem folgende Ergebnisse:

"Certain hyperactive ("copy-up") mutants of p can activate the g
origin more efficiently than the equivalent amount of wild-type
(wt) p."

http://jb.asm.org/cgi/reprint/177/23/6732.pdf


"...we used copy-up p mutants. These mutants contain single
amino acid substitutions and increase the copy number of core
plasmids two- to fourfold relative to the copy number at the
same level of wt p (60)."

http://jb.asm.org/cgi/reprint/177/22/6338.pdf

Oliver Annacker
Sweden
Local time: 19:45
Specializes in field
Native speaker of: German
PRO pts in category: 8
Grading comment
Vielen Dank, auch wenn ich nicht restlos überzeugt bin, dass hyperaktive Mutanten gemeint sind.
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