gene silencing

Hebrew translation: השתקת גנים

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:gene silencing
Hebrew translation:השתקת גנים

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13:58 Feb 9, 2010
English to Hebrew translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. biotech-info.net
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
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השתקת גנים
Definition:
מנגנון בעזרתו התא מבצע כיבוי קטעים גדולים של דנ"א כרומוזומלי. שיתוק הגן נעשה ע"י הפיכת קטע של דנ"א למצב שנקרא הטרוכרומטין ששעתוקו מוגבל. כל תא בגוף מקבל תבנית השתקה שונה ובכך מתבצעת הבדלה של תאים.
Selected response from:

Pavel Parkhomyuk (X)
Israel
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
4 +2השתקת גנים
Pavel Parkhomyuk (X)


  

Translations offered


1 day 18 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
השתקת גנים


Definition from own experience or research:
מנגנון בעזרתו התא מבצע כיבוי קטעים גדולים של דנ"א כרומוזומלי. שיתוק הגן נעשה ע"י הפיכת קטע של דנ"א למצב שנקרא הטרוכרומטין ששעתוקו מוגבל. כל תא בגוף מקבל תבנית השתקה שונה ובכך מתבצעת הבדלה של תאים.

Example sentence(s):
  • תופעת השתקת גנים בעזרת שימוש בטכנולוגיית RNA interference (RNAi) התגלתה זה מכבר כשיטה בעלת חשיבות רבה בחקר ובהבנה של תהליכים ביולוגיים שונים וכן ככלי בעל פוטנציאל רפואי רב עוצמה. - Hinet  
  • במחקרו הצליח ד"ר משורר להוכיח כי התמיינות לסוג תא מסוים גוררת אחריה השתקה של גנים שאינם רלוונטיים לתא מסוים זה. - הידען  
Pavel Parkhomyuk (X)
Israel
Local time: 04:28
Native speaker of: Native in RussianRussian, Native in HebrewHebrew
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Tzviya Levin Rifkind
1 day 6 hrs

Yes  Naty Schwartz
8 days
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