up-regulated and down-regulated gene expression

17:22 Aug 27, 2009
English to Latvian translations [Non-PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: up-regulated and down-regulated gene expression
cik saprotu šo terminu izmanto saistībā ar dažādu procesu regulāciju orgnaismā, bet kā pareizi iztulkot latviski? augšup un lejup regulācija?

Summary of answers provided
3jau jautāts un atbildēts. sk. saiti.



18 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
jau jautāts un atbildēts. sk. saiti.


Note added at 18 hrs (2009-08-28 12:07:58 GMT)

English term or phrase: upregulation of expression
For example, normal cellular proteins that control cell growth and differentiation, such as p53 (which is an example for a tumour suppressor gene), ras, c-met, myc, pRB, VHL, and HER-2/neu, can accumulate mutations resulting in upregulation of expression of these gene products thereby making them oncogenic (McCartey et al. Cancer Research 1998 15:58 2601-5; Disis et al. Ciba Found. Symp. 1994 187:198-211). These mutant proteins can be the target of a tumour specific immune response in multiple types of cancer.
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Latvian translation:ekspresijas pozitīva regulācija
Parasti runā par pozitīvu (sin. 'up-regulation') un negatīvu (sin. 'down-regulation') regulāciju.

Sk. http://raksti.daba.lv/referaati/2000/BNiedre/

Local time: 19:13
Native speaker of: Latvian
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