pan-tau

Polish translation: przeciwciała skierowane przeciwko wszystkim odmianom białka tau

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:pan-tau
Polish translation:przeciwciała skierowane przeciwko wszystkim odmianom białka tau
Entered by: Frank Szmulowicz, Ph. D.

16:29 Jun 4, 2018
English to Polish translations [PRO]
Medical - Medical (general) / badania kliniczne
English term or phrase: pan-tau
Opis badania klinicznego. Pełne zdanie brzmi tak:

"XXX is a pan-tau monoclonal antibody that has potential to treat Alzheimer’s disease."

Przeciwciało monoklonalne to wiadomo, biało tau też wiadomo, ale jak tu przetłumaczyć "pan-tau"? Będe wdzięczny za pomoc.
Letra
Poland
Local time: 12:53
przeciwciała skierowane przeciwko wszystkim odmianom białka tau
Explanation:
Pan means all or every:

The prefix "pan" normally relates to an antibody directed to a type of cell independently from its sub type or localization. Thus, pan endothelial cell marker is an antibody able to recognize all the endothelial cells regardless their subtypes, a pan-cytokeratin marker is directed to all the cytokeratins togheter, a pan-T-cell marker recognizes all the T lymphocytes regardless their types and antigen expression.
https://www.researchgate.net/post/what_does_a_pan_marker_mea...
Selected response from:

Frank Szmulowicz, Ph. D.
United States
Local time: 06:53
Grading comment
Dziękuję!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +2przeciwciała skierowane przeciwko wszystkim odmianom białka tau
Frank Szmulowicz, Ph. D.
Summary of reference entries provided
Marcin Pustkowski

Discussion entries: 1





  

Answers


34 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
przeciwciała skierowane przeciwko wszystkim odmianom białka tau


Explanation:
Pan means all or every:

The prefix "pan" normally relates to an antibody directed to a type of cell independently from its sub type or localization. Thus, pan endothelial cell marker is an antibody able to recognize all the endothelial cells regardless their subtypes, a pan-cytokeratin marker is directed to all the cytokeratins togheter, a pan-T-cell marker recognizes all the T lymphocytes regardless their types and antigen expression.
https://www.researchgate.net/post/what_does_a_pan_marker_mea...


Frank Szmulowicz, Ph. D.
United States
Local time: 06:53
Native speaker of: Native in EnglishEnglish, Native in PolishPolish
PRO pts in category: 1397
Grading comment
Dziękuję!

Peer comments on this answer (and responses from the answerer)
agree  Marcin Pustkowski: Otóż to!
3 mins
  -> Dziękuję Marcinie. Serdecznie pozdrawiam.

agree  magdadh
1 day 25 mins
  -> Dziękuję Magdo. Serdecznie pozdrawiam.
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Reference comments


15 mins peer agreement (net): +1
Reference

Reference information:
In the present study, we have tested the hypothesis that specificity of monoclonal antibodies directed to tau is an important determinant of efficacy in passive immunotherapy. MC1 recognizes an AD-specific tau conformational epitope, while DA31 and PHF1 are high-affinity antibodies detecting pan-tau or p-tau in both normal and Alzheimer’s brain.

Tau Passive Immunotherapy in Mutant P301L... (PDF Download


    Reference: http://tinyurl.com/y72q8x44
Marcin Pustkowski
Poland
Works in field
Native speaker of: Polish
PRO pts in category: 1069

Peer comments on this reference comment (and responses from the reference poster)
agree  Frank Szmulowicz, Ph. D.
19 mins
  -> Dziękuję!
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