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driver pathways

Portuguese translation: caminhos-chave

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:driver pathways
Portuguese translation:caminhos-chave
Entered by: Maria Teresa Borges de Almeida

14:36 Mar 3, 2018
English to Portuguese translations [PRO]
Medical - Medical (general) / Oncological care
English term or phrase: driver pathways
The phrase appears on a list as such:

"targeted therapeutics against driver pathways"

Any ideas?
Wendy Gosselin
Argentina
Local time: 14:45
caminhos-chave
Explanation:
Seria a minha sugestão em PT(pt), ver:

Mais recentemente, o próprio genoma dos tumores tem sido sequenciado, de modo a identificar-se todas as mutações existentes em todos os genes, para, posteriormente, ser possível a sua organização em algoritmos que permitam o reconhecimento dos “caminhos-chave”, que contribuem para o crescimento e sobrevivênciado cancro, e o desenvolvimento de terapêuticas direcionadas contra esses mesmos “caminhos” (Stratton,
Campbell & Futreal, 2009; Vollan & Caldas, 2011; Mukherjee, 2012; Alexandrov
et al., 2013).
https://www.repository.utl.pt/bitstream/10400.5/10096/1/Clas...
Selected response from:

Maria Teresa Borges de Almeida
Portugal
Local time: 18:45
Grading comment
Gracias!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1caminhos-chave
Maria Teresa Borges de Almeida
3vias de mutações driver (ou mutações condutoras)
Cátia Santana
Summary of reference entries provided
Interessante descrição
Ana Vozone

  

Answers


18 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
caminhos-chave


Explanation:
Seria a minha sugestão em PT(pt), ver:

Mais recentemente, o próprio genoma dos tumores tem sido sequenciado, de modo a identificar-se todas as mutações existentes em todos os genes, para, posteriormente, ser possível a sua organização em algoritmos que permitam o reconhecimento dos “caminhos-chave”, que contribuem para o crescimento e sobrevivênciado cancro, e o desenvolvimento de terapêuticas direcionadas contra esses mesmos “caminhos” (Stratton,
Campbell & Futreal, 2009; Vollan & Caldas, 2011; Mukherjee, 2012; Alexandrov
et al., 2013).
https://www.repository.utl.pt/bitstream/10400.5/10096/1/Clas...


Maria Teresa Borges de Almeida
Portugal
Local time: 18:45
Specializes in field
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 1304
Grading comment
Gracias!

Peer comments on this answer (and responses from the answerer)
agree  Margarida Ataide
2 hrs
  -> Obrigada, Margarida!
Login to enter a peer comment (or grade)

27 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
vias de mutações driver (ou mutações condutoras)


Explanation:
Sugestão:

Acredito que "driver" esteja se referindo a "driver mutations"

https://www.ncbi.nlm.nih.gov/pubmed/21129606

http://sopterj.com.br/profissionais/_revista/2016/n_02/7-mut...

Cátia Santana
Brazil
Local time: 14:45
Specializes in field
Native speaker of: Portuguese
PRO pts in category: 27
Login to enter a peer comment (or grade)




Reference comments


29 mins
Reference: Interessante descrição

Reference information:
https://books.google.pt/books?id=2UE7DwAAQBAJ&pg=PA174&lpg=P...

Ana Vozone
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 67
Login to enter a peer comment (or grade)



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