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pcy mice

Russian translation: мыши линии pcy

19:20 Nov 3, 2013
English to Russian translations [PRO]
Medical - Biology (-tech,-chem,micro-)
English term or phrase: pcy mice
Уважаемый коллеги!

Помогите, пожалуйста, правильно перевести термин:

In **pcy mice**,37 an animal model of human nephronophthisis,
drug administration in diet showed a dose-dependent inhibition of the progression of PKD, as reflected by decreases in kidney weight, kidney cyst volume, kidney fibrosis volume, and mitotic index.

Благодарю за помощь!
Irina Levchenko
Local time: 14:21
Russian translation:мыши линии pcy
Explanation:
Полное название линии - DBA/2-pcy/pcy, а сокращенно ее называют просто pcy

Вот описание линии:
... we investigated the expression of MAPK in DBA/2-pcy/pcy (pcy) mice, a murine model of childhood PKD, juvenile nephronophthisis. Pcy mice have a missense mutation in NPHP3, the causal gene for human adolescent-type nephronophthisis (10). At an early stage, pcy mice are characterized by cysts that are derived predominantly from collecting ducts and urine concentration defect... Later in the course, all nephron segments become cystically dilated.
http://jasn.asnjournals.org/content/17/6/1604.full.pdf
Selected response from:

Natalie
Poland
Local time: 13:21
Grading comment
Большое спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1мыши линии pcy
Natalie


  

Answers


15 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
мыши линии pcy


Explanation:
Полное название линии - DBA/2-pcy/pcy, а сокращенно ее называют просто pcy

Вот описание линии:
... we investigated the expression of MAPK in DBA/2-pcy/pcy (pcy) mice, a murine model of childhood PKD, juvenile nephronophthisis. Pcy mice have a missense mutation in NPHP3, the causal gene for human adolescent-type nephronophthisis (10). At an early stage, pcy mice are characterized by cysts that are derived predominantly from collecting ducts and urine concentration defect... Later in the course, all nephron segments become cystically dilated.
http://jasn.asnjournals.org/content/17/6/1604.full.pdf


Natalie
Poland
Local time: 13:21
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 4009
Grading comment
Большое спасибо!

Peer comments on this answer (and responses from the answerer)
agree  Igor_2006
8 hrs
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