a reversible ring closure within the side chain of rosuvastatin

Russian translation: обратимое замыкание цикла в боковой цепи розувастатина

09:25 Sep 26, 2019
English to Russian translations [PRO]
Medical - Chemistry; Chem Sci/Eng / chemical structure
English term or phrase: a reversible ring closure within the side chain of rosuvastatin
Metabolism
Rosuvastatin undergoes only limited metabolic degradation.
In a study administering radiolabelled rosuvastatin at a dose of 5 mg/kg, it could be shown, that the unchanged compound accounted for 88.3% of biliary radioactivity and 87.5% of faecal radioactivity excretion.
A pentenoic acid derivative was identified as main oxidative metabolite, both, in plasma and liver, while 5S-lactone (a reversible ring closure within the side chain of rosuvastatin) was identified as a minor metabolite.
Deliia
Russian Federation
Local time: 06:46
Russian translation:обратимое замыкание цикла в боковой цепи розувастатина
Explanation:
5S-лактон (образующийся в результате обратимого замыкания цикла в боковой цепи розувастатина)
Selected response from:

Igor Andreev
Local time: 06:46
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1обратимое замыкание цикла в боковой цепи розувастатина
Igor Andreev


  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
обратимое замыкание цикла в боковой цепи розувастатина


Explanation:
5S-лактон (образующийся в результате обратимого замыкания цикла в боковой цепи розувастатина)

Igor Andreev
Local time: 06:46
Native speaker of: Native in RussianRussian
PRO pts in category: 155
Grading comment
Спасибо!

Peer comments on this answer (and responses from the answerer)
agree  Oleksandr Mandzhos: Спасибо
7 hrs
  -> Спасибо и Вам!
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.


See also:

Your current localization setting

English

Select a language

Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search