large cell anaplastic lymph*** cells

20:58 Nov 22, 2008
This question was closed without grading. Reason: No acceptable answer

English to Russian translations [PRO]
Medical - Medical (general)
English term or phrase: large cell anaplastic lymph*** cells
The positive staining tissue components (***large cell anaplastic lymph cells***, mononuclear or multinucleated Reed Sternberg cells), are used to confirm that the antibody was applied and the instrument functioned properly.

Есть подозрение, что должно быть не lymph, а lymphoma. Или какие другие версии?
Marina Mrouga
Local time: 17:21

Summary of answers provided
derugin (X)
4large anaplastic lymphoid cells

Discussion entries: 2



1 hr   confidence: Answerer confidence 5/5

lymphatic cells, not lymphoma cells.

derugin (X)
Local time: 04:21
Specializes in field
Native speaker of: Native in RussianRussian, Native in EnglishEnglish
PRO pts in category: 31
Notes to answerer
Asker: тогда, пожалуйста, переведите всю фразу, вставив туда две cell

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14 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
large anaplastic lymphoid cells

слово "cell" после "large" лишнее...

В 2007 г. редактировала книгу серии РФТ "Гематология" под редакцией академика А.И. Воробьева (выпуск планируется на 2008-2009 гг.).
Привожу цитату из главы "Т-КЛЕТОЧНЫЕ И NK-КЛЕТОЧНЫЕ ЛИМФАТИЧЕСКИЕ ОПУХОЛИ" (Ю. Е. Виноградова, А.И. Воробьев):
"Первичная кожная анаплазированная крупноклеточная лимфома (CD30+)
- Гистология. В биоптате кожи выявляется диффузный полиморфный инфильтрат, который распространяется на поверхностные и глубокие слои дермы, подкожную ткань, эпидермис. В биоптате лимфоузла наблюдается увеличенное количество крупных атипичных Т-клеток, а также участки изъязвления и некроза. Встречаются ***анаплазированные лимфоидные клетки*** с многодольчатыми ядрами, а также большие анаплазированные двуядерные клетки с нуклеолами, напоминающие клетки Березовского—Штернберга".

They consist of a proliferation of predominantly ***large lymphoid cells*** with strong expression of the cytokine receptor CD30 (>75%)ю

Lymphoma with polymorphic morphology composed of ***large atypical lymphoid cells*** with multi lobated and horseshoe shaped nuclei (hallmark cells). Background cell infiltrate may contain neutrophils, eosinophils, small lymphoid cells and macrophages. Two types of clinical presentation are recognized; Aggressive systemic form (nodes and extranodal type) and indolent primary cutaneous form.


CD30+ ***large anaplastic lymphoid cells*** are seen in anaplastic large cell lymphoma (ALCL), and also in lymphomatoid papulosis (LyP) and other lymphoproliferative disorders.

Anaplastic large cell lymphoma (ALCL) represents a generally recognized group of large cell lymphomas. Defining features consist of a proliferation of predominantly ***large lymphoid cells*** with strong expression of the cytokine receptor CD30 and a characteristic growth pattern. ...The small cell variant11 is characterized by a mixture of small, medium-sized, and large lymphoid cells (Figure 2).

Nieborowska-Skorska M, Slupianek A, Xue L, et al. Role of signal transducer and activator of transcription 5 in nucleophosmin/anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Cancer Res. 2001;61: 6517-6523.

Chan JK. The perivascular cuff of ***large lymphoid cells***: a clue to diagnosis of anaplastic large cell lymphoma. Int J Surg Pathol. 2000;8:153–156.

Example sentence(s):
  • large anaplastic lymphoid cells of Anaplastic Large Cell Lymphoma (ALCL)
  • The positive staining tissue components (large anaplastic lymphoid cells, mononuclear or

Russian Federation
Local time: 17:21
Specializes in field
Native speaker of: Russian
PRO pts in category: 64
Notes to answerer
Asker: Да, либо так, либо лимфома, т.к. конструкция "клетки лимфомы" встречается неоднократно. Но явно есть ошибка

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