sub-therapeutic pharmacokinetic tail

Russian translation: период субтерапевтической концентрации

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:sub-therapeutic pharmacokinetic tail
Russian translation:период субтерапевтической концентрации
Entered by: Kateryna Melnychenko

02:22 Nov 8, 2019
English to Russian translations [PRO]
Medical - Medical (general) / HIV, исследования новых препаратов
English term or phrase: sub-therapeutic pharmacokinetic tail
Does a long-acting injectable have a prolonged sub-therapeutic pharmacokinetic tail if dosing is interrupted / terminated?
Kateryna Melnychenko
Canada
Local time: 13:24
период субтерапевтической концентрации
Explanation:
или период субтерапевтической экспозиции

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Note added at 3 час (2019-11-08 06:17:10 GMT)
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Исходя из этого определения pharmacokinetic “tail”:

"All PrEP medications have some amount of pharmacokinetic “tail”—a period when the drug is still present in the body but unlikely to still be highly effective for prevention (although still potentially able to drive HIV resistance); longer-acting formulations in general have longer tails, with clinical and virologic consequences still to be determined."

https://academic.oup.com/jid/advance-article/doi/10.1093/inf...
Selected response from:

Doctor Alex
Local time: 20:24
Grading comment
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Summary of answers provided
4период субтерапевтической концентрации
Doctor Alex


  

Answers


3 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
период субтерапевтической концентрации


Explanation:
или период субтерапевтической экспозиции

--------------------------------------------------
Note added at 3 час (2019-11-08 06:17:10 GMT)
--------------------------------------------------

Исходя из этого определения pharmacokinetic “tail”:

"All PrEP medications have some amount of pharmacokinetic “tail”—a period when the drug is still present in the body but unlikely to still be highly effective for prevention (although still potentially able to drive HIV resistance); longer-acting formulations in general have longer tails, with clinical and virologic consequences still to be determined."

https://academic.oup.com/jid/advance-article/doi/10.1093/inf...

Doctor Alex
Local time: 20:24
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 590
Grading comment
Спасибо!
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