primary treatment policy estimand

14:04 Aug 9, 2018
This question was closed without grading. Reason: No acceptable answer

English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: primary treatment policy estimand
The imputation model for the missing observations in both the study drug and placebo (control) groups will be constructed from the control group only (missing not at random [MNAR]).
This assumes that efficacy results post withdrawal, for subjects who withdraw, would have mirrored those seen in the placebo group and thus lose any potential study drug treatment benefit.
Additional estimands/tests of treatment effect, beyond the primary treatment policy estimand, may be addressed, including exploring other ways of handling missing values, such as fitting repeated measures mixed models.
Summary statistics will present the number of observed values and will then be based on the nonmissing values for the open-label extension phase.

Если «estimand» — это «оцениваемая величина/параметр», то как при переводе его можно связать с «primary treatment policy»?
Заранее спасибо!
Russian Federation
Local time: 02:16

Discussion entries: 4


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