human immunoglobulin (Ig) G1-derived Fc of the za allotype

Russian translation: Fc-фрагмент человеческого иммуноглобулина IgG1 аллотипа za

05:02 May 19, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: human immunoglobulin (Ig) G1-derived Fc of the za allotype
CIDP may occur at any age, but it is more common in the fifth and sixth decades.
Relapsing course is associated with younger age of patients (third and fourth decades).

Efgartigimod (ARGX-113) is a human immunoglobulin (Ig) G1-derived Fc of the za allotype that binds with nanomolar affinity to human neonatal Fc receptor (FcRn).

fgartigimod encompasses IgG1 residues D220-K447 (European Union [EU] numbering scheme) and has been modified with the so-called ABDEGTM technology (ABDEGTM = antibody that enhances IgG degradation) to increase its affinity for FcRn at both physiological and acidic pH.
Maxim Polukhin
Local time: 22:15
Russian translation:Fc-фрагмент человеческого иммуноглобулина IgG1 аллотипа za
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Natalie
Poland
Local time: 20:15
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4Fc-фрагмент человеческого иммуноглобулина IgG1 аллотипа za
Natalie


  

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3 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
human immunoglobulin (ig) g1-derived fc of the za allotype
Fc-фрагмент человеческого иммуноглобулина IgG1 аллотипа za


Explanation:
*

Natalie
Poland
Local time: 20:15
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 11625
Grading comment
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