disease-modifying anti-rheumatic drug (DMARD)

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00:54 May 26, 2020
English to Slovak translations [PRO]
COVID-19 - Medical - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism
English term or phrase: disease-modifying anti-rheumatic drug (DMARD)
Definition from National Center for Biotechnology Info.:
Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the treatment of other disorders including connective tissue disease such as systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and Sjogren syndrome (SS), as well as in treatment of inflammatory myositis, vasculitis, uveitis, inflammatory bowel disease, and some types of cancers.

Example sentence(s):
  • Hydroxychloroquine has been available since 1955 as an antimalarial drug. I have at least 6 patients at the pharmacy who have used hydroxychloroquine to manage their rheumatoid arthritis, lupus, and Crohn disease. If you were sitting in my pharmacology class, I’d tell you that it is an antimalarial used as a disease-modifying antirheumatic drug (DMARD). I would tell you it is a cheap drug with good efficacy for some and also that it is 1 of 2 DMARDs that are safe to use in patients with liver failure. You would also learn that it may cause deposition of the drug in the melanin layer of the cones in the retina, underscoring the need for annual eye exams. MJH Life Sciences
  • DMARDs Not Linked to Poor Outcomes in SARS-CoV-2 RA Patients Rheumatology Network
  • The analysis of performance measures for rheumatoid arthritis (RA) care have allowed to identify gaps in care that include suboptimal use of disease-modifying anti-rheumatic drugs (DMARDs), according to a study published in Arthritis Care & Research. Rheumatology Advisor
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Question posted on behalf of translation team:
GBK medical and pharma specialists

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Summary of translations provided
4 +1chorobu modifikujúce antireumatiká
Stefan Pecen


Translations offered

1 day 3 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
chorobu modifikujúce antireumatiká

Definition from Aktuálna farmakoterapia:
chorobu modifikujúci efekt majú syntetické bazálne lieky (DMARD: metotrexát, sulfasalazín, antimalariká, leflunomid) a biologické (etanercept, infliximab, adalimumab, golimumab, certolizumab
pegol, rituximab, abatacept, tocilizumab, anakinra, belimumab, ustekinumab)

Example sentence(s):
  • Pod bazálnou liečbou rozumieme použitie chorobu modifikujúcich liekov (DMARD – Disease modifying antirheumatic drugs), ktoré zásahom do imunopatogenetických procesov sú schopné ovplyvniť laboratórnu aj klinickú aktivitu a majú vplyv aj na rtg progresiu choroby - Aktuálna farmakoterapia  
Stefan Pecen
Local time: 04:12
Native speaker of: Native in SlovakSlovak
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Beata Fabova
29 days
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