co-crystals

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00:54 Sep 4, 2020
English to Slovak translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
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Summary of translations provided
5kokryštál
Alžbeta Takácsová


  

Translations offered


14 hrs   confidence: Answerer confidence 5/5
kokryštál


Definition from klinickafarmakologie.cz:
kokryštál = Je to multikomponentná molekula typu hostiteľ (aktívna molekula) a hosť ( kokryštalizačný partner), vytvorená z dvoch alebo viacerých zložiek, ktoré sú v čistom stave a pri izbovej teplote pevné (8).

Example sentence(s):
  • ...44,74 mg kokryštálu agomelatín-kyselina citrónová... - adc.sk  
Alžbeta Takácsová
Slovakia
Local time: 04:00
Native speaker of: Native in SlovakSlovak
PRO pts in category: 64
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