substrain

Spanish translation: subcepa

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:substrain
Spanish translation:subcepa
Entered by: Neil Ashby

14:38 Jan 10, 2020
English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: substrain
Buenos días, tengo que hacer la traducción de los párrafos que copio a continuación. En ellos aparece "sub-strain" strain=cepa tengo entendido, no he visto hasta ahora substrain pero podría ser como "cepa secundaria",,.... GRacias


Abstract
C57BL/6J and C57BL/6N inbred mice are widely, and often interchangeably, used for stem cell research; yet, these substrains harbor discrete genetic differences that can cause phenotypic disparities. In this issue of Stem Cell Reports, Morales-Hernández et al. identify one particular difference—disruption of Nicotinamide Nucleotide Transhydrogenase (Nnt)—that increases reactive oxygen exposure and impairs hematopoietic progenitor cell function in C57BL/6J, as compared to C57BL/6N, mice.


Main Text
The laboratory mouse has been a highly valuable tool for biological and biomedical research, and the inbred C57BL/6 strain is one of the most widely used across the globe, thanks in part to its fecundity, lifespan, and relatively low predisposition to spontaneous tumors. The origins of the C57BL/6 strain date back to the early 20th century, when Miss Abbie Lathrop began breeding mice on her farm in Granby, Massachusetts. It was there that Lathrop established and maintained several colonies of mice, some of which she later sold to the Harvard geneticist William Castle. In 1921, Castle’s student, C.C. Little (who later went on to found the Jackson Laboratory), crossed female mouse 57 to male mouse 52 from Lathrop’s stocks to generate progeny termed C57 Black (C57BL). Little continued propagating these mice until he established the C57BL/6J substrain at the Jackson Laboratory in 1948. In 1951, a colony of C57BL/6J mice was transferred to the National Institutes of Health (NIH), establishing the C57BL/6N substrain, which was later distributed to several companies including Charles River Laboratories (C57BL/6NCrl), Harlan Sprague Dawley (C57BL/6NHsd), and Taconic Farms (C57BL/6NTac).
sebaspedlp
Argentina
Local time: 23:16
subcepa
Explanation:
Una cepa endocriada se puede dividir en subcepas y sublíneas. La subcepa se forma cuando dos colonias de la misma cepa de ratón son separadas después de la vigésima generación, pero antes de la generación cuarenta de la endocría, o cuando se produce una mutación en una colonia. Las subcepas se designan con un número o una letra luego del nombre de la cepa parental y separada por una barra. La letra o número designan al individuo o las instituciones que mantienen dichas subcepas.

https://geneticabioterio.wordpress.com/animestandarizados/




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Note added at 29 mins (2020-01-10 15:07:57 GMT)
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Microbiological characterization of cell metabolism in different culture media of Mycobacterium bovis BCG Moreau subcepa containing the opc gene of Neisseria meningitidis. Caracterización microbiológica del metabolismo celular en diferentes medios de cultivo de la subcepa Mycobacterium bovis BCG Moreau que contiene el gen opc de Neisseria meningitidis.

https://www.researchgate.net/publication/327895660_Microbiol...
Selected response from:

Neil Ashby
Spain
Local time: 03:16
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +2subcepa
Neil Ashby


  

Answers


29 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
subcepa


Explanation:
Una cepa endocriada se puede dividir en subcepas y sublíneas. La subcepa se forma cuando dos colonias de la misma cepa de ratón son separadas después de la vigésima generación, pero antes de la generación cuarenta de la endocría, o cuando se produce una mutación en una colonia. Las subcepas se designan con un número o una letra luego del nombre de la cepa parental y separada por una barra. La letra o número designan al individuo o las instituciones que mantienen dichas subcepas.

https://geneticabioterio.wordpress.com/animestandarizados/




--------------------------------------------------
Note added at 29 mins (2020-01-10 15:07:57 GMT)
--------------------------------------------------

Microbiological characterization of cell metabolism in different culture media of Mycobacterium bovis BCG Moreau subcepa containing the opc gene of Neisseria meningitidis. Caracterización microbiológica del metabolismo celular en diferentes medios de cultivo de la subcepa Mycobacterium bovis BCG Moreau que contiene el gen opc de Neisseria meningitidis.

https://www.researchgate.net/publication/327895660_Microbiol...

Neil Ashby
Spain
Local time: 03:16
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 177
Notes to answerer
Asker: muchas gracias, saludos


Peer comments on this answer (and responses from the answerer)
agree  José Huarancca
1 hr
  -> Thanks José, again! ;@)

agree  Chema Nieto Castañón
2 days 7 hrs
Login to enter a peer comment (or grade)



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