escrutinizador hipersensible de alto rendimiento
Es el procedimiento que se utiliza para el escrutinio de la luminiscencia, fluorescencia, fuentes de luz, filtros, detectores, etc. en pruebas de laboratorio.
Ver los siguientes enlaces:
Cellomics® is automating drug discovery through a unique, cell-based product platform that combines ultra high throughput primary screening with complete systems for high content screening, including fluorescent reagents, kits, and cell lines, multiparametric assays, cell analysis instrumentation, informatics and cellular bioinformatics
Specifically developed to meet the challenges of HTS, Analyst™ HT delivers unparalleled multi-mode assay detection performance in a system optimized for seamless integration into the automated HTS bioassay environment. Developed at LJL BioSystems, Analyst HT is now available from Molecular Devices Corporation.
Multi-mode Assay Versatility
Analyst HT offers detection based on:
High Efficiency Fluorescence Polarization (HEFP™)
Time-resolved fluorescence resonance energy transfer (TR-FRET)
Absorbance (epi- and trans-)
Each assay detection mode has been optimized to deliver enhanced performance in terms of sensitivity, dynamic range, signal-to-noise and cross-talk.
Only Analyst HT delivers uncompromising sensitivity and dynamic range in all fluorescence-based assay detection modes; regardless of whether the assays run in 96- or 384-well microplates. And with HE™ Microplates, Analyst can reduce compound and reagent consumption up to 10-fold.
Analyst HT achieves this performance with SmartOptics™, a unique system (patents pending) which selects and configures light sources, filters, detectors, and optical paths to insure maximum assay performance.
75,000 Data Points a Day — As a Workstation
Analyst HT operates as a workstation with an integrated stacker, feeding plates from a 20-plate magazine. These magazines are fully compatible with Titertek®* M Series washers and dispensers, eliminating manual restacking. The three-position stacker allows plates to be loaded into the instrument without removing the magazines. And with Analyst HT’s fast read speed, almost 200 384-well plates can be read in less than nine hours. That’s over 75,000 data points!
Born to Run with Robots
Analyst HT is optimized for seamless integration into robotic environments, including those from Beckman Coulter, Zymark, CRS and Robocon. The rugged, high-speed plate mechanism of Analyst HT reliably enables screening of over 75,000 wells per day.
Detection Limits at a Glance
Mode Method Detection Limit
Fluorescence intensity <5 pM fluorescein in 96- or 384-well
Fluorescence polarization 10 mP std. dev, at 100 pM Fluorescein in 96- or 384-well
Time-resolved fluorescence <100 fM europium in 96- or 384-well
Luminescence <10,000 photons/sec. in 96-well
*Titertek is a registered trademark of Titertek Corporation.
Local time: 07:28
Native speaker of: Spanish
PRO pts in pair: 721