allostery

Swedish translation: allosteri

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:allostery
Swedish translation:allosteri

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19:25 Mar 9, 2009
English to Swedish translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Genetics
English term or phrase: allostery
Definition from Biochemical Society:
Property of some proteins by which spatially separate functional sites in the molecule can communicate with each other via movements transmitted through the structure.

Example sentence(s):
  • Oligomerization enables cooperativity between multiple binding sites, a property referred to as allostery or allosteric regulation of enzymes (yet again, single polypeptide, multi-domain proteins show allosteric behavior). whatislife.com
  • The sequential model of allostery holds that subunits are not connected in such a way that a conformational change in one induces a similar change in the others. Thus all enzyme subunits need not exist in the same conformation. bio-medicine.org
  • It also follows that allostery is common and that homologous proteins can have different allosteric mechanisms. nature.com
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allosteri
Definition:
"reglering av enzymaktivitet genom att en liten molekyl (en allosterisk effektor eller allosterisk regulator) binds till ett allosteriskt centrum, som är ett annat ställe på enzymmolekylen än det katalytiska centrumet. Allosteriska effektorer kan vara inhibitorer eller aktivatorer, dvs. ha en hämmande eller stimulerande inverkan på enzymets aktivitet. "

Eget tillägg: NE:s definition är egentligen lite för snäv, eftersom det inte behöver röra sig om ett enzym utan kan vara ett annat biologiskt aktivt ämne. Ett klassiskt exempel är hemoglobin, där de fyra subenheternas påverkar varandras syreaffinitet genom en allaosteriks mekanism.
Selected response from:

Folke Nettelblad
Sweden
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Summary of translations provided
5 +2allosteri
Folke Nettelblad


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32 mins   confidence: Answerer confidence 5/5 peer agreement (net): +2
allosteri


Definition from Nationalencyklopedin:
"reglering av enzymaktivitet genom att en liten molekyl (en allosterisk effektor eller allosterisk regulator) binds till ett allosteriskt centrum, som är ett annat ställe på enzymmolekylen än det katalytiska centrumet. Allosteriska effektorer kan vara inhibitorer eller aktivatorer, dvs. ha en hämmande eller stimulerande inverkan på enzymets aktivitet. "

Eget tillägg: NE:s definition är egentligen lite för snäv, eftersom det inte behöver röra sig om ett enzym utan kan vara ett annat biologiskt aktivt ämne. Ett klassiskt exempel är hemoglobin, där de fyra subenheternas påverkar varandras syreaffinitet genom en allaosteriks mekanism.

Example sentence(s):
Folke Nettelblad
Sweden
Local time: 09:04
Native speaker of: Native in SwedishSwedish
PRO pts in category: 62

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Anna Klotz
3 days 11 hrs

Yes  Angelica Kjellström
49 days
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