Enzyme Linked Immunosorbent Assay (ELISA)

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00:55 Aug 12, 2020
English to Swedish translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Medical (general)
English term or phrase: Enzyme Linked Immunosorbent Assay (ELISA)
Definition from Pharma IQ:
Enzyme Linked Immunosorbent Assay (ELISA) is defined as an assay that relies on an enzymatic conversion reaction and is used to detect the presence of specific substances (such as enzymes or viruses or antibodies or bacteria). During the procedure the test material or sample is exposed to a complex of an enzyme linked to an antibody specific to the disease or substance being tested for; when the enzyme and the antigen-antibody complex bind, a color indicator or other easily recognizable sign occurs.

Example sentence(s):
  • The elementary enzyme-linked immunosorbent assay (ELISA), or enzyme immunoassay (EIA), is different from the other available antibody-based techniques in a way that in a polystyrene (96 or 384) multi-well plate (which is considered good for protein binding) the binding to solid surface sequentially results in the identification of specific reactions excluding the non-specific ones. MyBioSource
  • Of all the ELISA formats, direct ELISA assays are the simplest and quickest to perform, however, they are the least sensitive. AAT Bioquest
  • Research ELISA (Enzyme-Linked Immunosorbent Assay) market worldwide is projected to grow by US$143. 7 Billion, driven by a compounded growth of 4%. ELISA Kits, one of the segments analyzed and sized in this study, displays the potential to grow at over 3. GlobeNewswire
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Summary of translations provided
5ELISA (enzymkopplad immunadsorberande analys)
Anna Smith


  

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1 day 8 hrs   confidence: Answerer confidence 5/5
ELISA (enzymkopplad immunadsorberande analys)


Definition from Svensk MeSH, Karolinska Institutet:
En immunanalysmetod som utnyttjar en antikropp med enzymmarkör, t ex pepparrotsperoxidas. Då antingen enzymet eller antikroppen binds till ett adsorberande substrat behåller båda sin biologiska aktivitet. Förändringen i enzymaktivitet till följd av enzym-antikropp-antigenreaktionen är proportionell mot mängden antigen och kan mätas med spektrofotometri eller med blotta ögat. Det har utvecklats många varianter av metoden.

Example sentence(s):
  • Enzymkopplad immunadsorberande analys, eng. Enzyme-Linked ImmunoSorbent Assay (ELISA) används för att kvantifiera och detektera en antikropp eller ett antigen. Principen är att ett antigen binds till väggar och / eller botten i brunnarna i en mikrotiterplatta. - Wikipedia  
  • Metoden heter Elisa, enzymkopplad immunadsorberande analys, och är en screeningmetod, vilket är det första steget i behandlingen av ett blodprov som går till droganalys på Rättsmedicinalverkets rättskemiska laboratorium i Linköping. - Life Science Sweden  
  • Lämpliga metoder är IgE-bindningsanalyser, såsom radioallergosorbenttest (Rast), enzymatisk bestämning i fastfassystem (EAST, Enzyme Allergosorbent Test), enzymkopplad immunadsorberande analys (Elisa) och elektrofores följt av immunoblotting med specifika sera som innehåller IgE. - OJEU  

Explanation:
It's sometimes called "Enzymkopplad immunabsorberande analys", spelling it with a "b" rather than a "d". Both versions are OK.
Anna Smith
Switzerland
Local time: 02:32
Native speaker of: Native in SwedishSwedish
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