gene silencing

Turkish translation: gen susturma

English term or phrase:gene silencing
Turkish translation:gen susturma

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12:55 Feb 9, 2010
English to Turkish translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms.
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
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gen susturma
Birçok tıbbi makalede bu şekilde dilimize girmiştir.
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Murat Uzum
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Summary of translations provided
5 +2gen susturma
Murat Uzum


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41 mins   confidence: Answerer confidence 5/5 peer agreement (net): +2
gen susturma

Definition from Google Documents:
Birçok tıbbi makalede bu şekilde dilimize girmiştir.

Example sentence(s):
  • Ortadoğu Teknik Üniversiteli (ODTÜ) araştırmacılar, tahılda rekoltenin düşmesine neden olan buğdayda sarı pas, arpada külleme hastalığında rol alan bir genin işlevini gen susturma yöntemiyle tanımlamayı başardı. - Genç Ziraat  
  • ABD'li ve Alman bilim adamları, insan vücudunun yapıtaşlarından RNA sayesinde 'gen susturma' adı verilen yöntemle hastalıklı genlerin 'kapatılabileceğini' açıkladı. - Gen Bilim  
  • RNA interferans, çift iplikçikli RNA'nın hücreye girdiğinde homoloğu olan mRNA'nın yıkılması ile sonuçlanan transkripsiyon sonrası gen susturma mekanizmasıdır - Pamukkale Üniversitesi SBE  
Murat Uzum
Local time: 07:16
Native speaker of: Native in TurkishTurkish
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  ceren gunger
7 hrs
  -> Teşekkür ederim Ceren Hanım.

Yes  Nilgün Bayram
10 days
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