foot-pad assay

English translation: mouse foot-pad

17:48 Apr 7, 2005
English to English translations [PRO]
Medical - Medical (general)
English term or phrase: foot-pad assay
Delayed hypersensitivity to simian virus 40 tumor cells in BALB-c mice
demonstrated by a radioisotopic foot-pad assay.
[what is foot-pad assay? What foot and pad mean in this context?]
nnowak (X)
English translation:mouse foot-pad
Explanation:
This assay is used to measure delayed type hypersensitivity.

Foot-pad = the fleshy underpart of the foot of the mouse

“The quantitative mouse foot-pad model was used to assay the Delayed-Type Hypersensitivity (DTH) cell-mediated immune response to extracts of purified endospores and sporangia of R. seeberi. Histological examination was used to confirm that the foot-pad reactions were compatible with DTH reactions in the mouse. We report that sonically disintegrated rhinosporidial endospores/sporangia induced DTH responses in the foot-pads of sensitized mice which were comparable in intensity and histological profile to that induced by sheep red blood cells in SRBC sensitized mice.” http://www.springerlink.com/app/home/contribution.asp?wasp=0...
Selected response from:

Elizabeth Rudin
United Kingdom
Local time: 05:29
Grading comment
Thank you very much.
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +4mouse foot-pad
Elizabeth Rudin


  

Answers


12 mins   confidence: Answerer confidence 5/5 peer agreement (net): +4
mouse foot-pad


Explanation:
This assay is used to measure delayed type hypersensitivity.

Foot-pad = the fleshy underpart of the foot of the mouse

“The quantitative mouse foot-pad model was used to assay the Delayed-Type Hypersensitivity (DTH) cell-mediated immune response to extracts of purified endospores and sporangia of R. seeberi. Histological examination was used to confirm that the foot-pad reactions were compatible with DTH reactions in the mouse. We report that sonically disintegrated rhinosporidial endospores/sporangia induced DTH responses in the foot-pads of sensitized mice which were comparable in intensity and histological profile to that induced by sheep red blood cells in SRBC sensitized mice.” http://www.springerlink.com/app/home/contribution.asp?wasp=0...

Elizabeth Rudin
United Kingdom
Local time: 05:29
Specializes in field
Native speaker of: Native in HungarianHungarian, Native in RomanianRomanian
PRO pts in category: 60
Grading comment
Thank you very much.

Peer comments on this answer (and responses from the answerer)
agree  juvera: Impressive.
2 hrs
  -> Thank you :)

agree  Jörgen Slet
3 hrs
  -> Thanks, Jörgen.

agree  Robert Donahue (X): Impressive indeed+++ She modestly retorted : )
4 hrs
  -> Thanks, Robert. It sounds more complicated than it is... :)

agree  Martinique
16 hrs
  -> Thank you, Martinique.
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