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progenitor cell

English translation: Read below

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23:13 Aug 22, 2001
English to English translations [PRO]
Medical - Biology (-tech,-chem,micro-)
English term or phrase: progenitor cell
Is "progenitor cell" an exact synonym for "stem cell"? Reference required!
Sven Petersson
Sweden
Local time: 10:48
English translation:Read below
Explanation:
Maybe this could clarify your doubt a bit...

Stem Cell Assay

There are certain cells in the bone marrow whose only function is to produce all the different types of cells in the blood. These cells are called hematopoietic stem cells and when they divide, they produce daughter cells called progenitor cells. Both the stem and progenitor cell groups are equally important in the patient’s recovery process following a stem cell transplant. There are two methods available that can be used to determine the adequacy of the stem cell collection for transplantation. Our laboratory performs both of these assays, the colony-forming unit (CFU) and CD34 analysis.

Colony Forming Unit Assay
The CFU assay involves taking a small portion of the stem cell collection and growing it in a culture. A single stem or progenitor cell in the sample will form a group of mature blood cells and these groups may be counted using a microscope. While the CFU assay is the best indicator of the ability of the stem cells to grow in the patient after transplantation, this testing procedure is not the ideal choice for most laboratories. The major drawback to the CFU test is that the results are not available for 2 weeks. Thus, the CFU test cannot be used to determine on a day to day basis when the patient has collected enough stem cells for transplantation...


http://www.nybloodcenter.org/4e1.htm

Selected response from:

Camara
United States
Local time: 04:48
Grading comment
I wish I could give you much more than 4 points. Your clear answer saved my day and protected me against egg in face!

THANK YOU VERY MUCH!

Sven.
4 KudoZ points were awarded for this answer

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Summary of answers provided
naRead below
Camara
naSee referencesjoanne_r


  

Answers


1 hr
See references


Explanation:
Here are some references showing it to be a synonym.

Hematopoietic Stem/Progenitor Cell Products -
http://www.fda.gov/cber/minutes/stem091098min.htm

temporal profiles of genes and their products involved in stem/progenitor cell
survival, proliferation, differentiation

www.the-scientist.com/yr2000/mar/lewis_p1_000306.html

joanne_r
Local time: 09:48
Login to enter a peer comment (or grade)

1 hr
Read below


Explanation:
Maybe this could clarify your doubt a bit...

Stem Cell Assay

There are certain cells in the bone marrow whose only function is to produce all the different types of cells in the blood. These cells are called hematopoietic stem cells and when they divide, they produce daughter cells called progenitor cells. Both the stem and progenitor cell groups are equally important in the patient’s recovery process following a stem cell transplant. There are two methods available that can be used to determine the adequacy of the stem cell collection for transplantation. Our laboratory performs both of these assays, the colony-forming unit (CFU) and CD34 analysis.

Colony Forming Unit Assay
The CFU assay involves taking a small portion of the stem cell collection and growing it in a culture. A single stem or progenitor cell in the sample will form a group of mature blood cells and these groups may be counted using a microscope. While the CFU assay is the best indicator of the ability of the stem cells to grow in the patient after transplantation, this testing procedure is not the ideal choice for most laboratories. The major drawback to the CFU test is that the results are not available for 2 weeks. Thus, the CFU test cannot be used to determine on a day to day basis when the patient has collected enough stem cells for transplantation...


http://www.nybloodcenter.org/4e1.htm



Camara
United States
Local time: 04:48
Native speaker of: Native in SpanishSpanish
PRO pts in category: 4
Grading comment
I wish I could give you much more than 4 points. Your clear answer saved my day and protected me against egg in face!

THANK YOU VERY MUCH!

Sven.
Login to enter a peer comment (or grade)




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Changes made by editors
May 30, 2008 - Changes made by Steffen Walter:
Field (specific)(none) » Biology (-tech,-chem,micro-)


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