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conformational change

Chinese translation: 構象變化

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English term or phrase:conformational change
Chinese translation:構象變化
Entered by: Gertrude Tsau
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21:54 Feb 11, 2009
English to Chinese translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Genetics
English term or phrase: conformational change
Definition from Biochemical Society:
Large, medium or small adjustment to the molecular shape/dynamics of a protein that may follow a change in environment or the specific recognition of another molecule.

Example sentence(s):
  • These observations indicate that heparin, in addition to causing aggregation, also induces a conformational change in tau in which reactive groups are unmasked or move closer leading to the DSS cross-linking of 72- and 83-kDa species. jbc online
  • At low pH, the hemagglutinin (HA) of influenza virus undergoes an irreversible conformational change that potentiates its essential membrane fusion function. The Rockefeller University Press
  • To develop the antibody chip for detecting the Bax conformational change, we immobilized Bax monoclonal antibody 6A7, which recognizes only a conformationally changed Bax protein on a gold surface. Elsevier Inc.
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Gertrude Tsau
United States
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Summary of translations provided
4 +4構象變化
Gertrude Tsau
Yulin Chang


Translations offered

1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +4

Definition from 維基百科:

Example sentence(s):
  • 但是多年來蛋白質變性的大量研究通常局限于蛋白分子的構象變化,很少把分子的構象變化 與其活性變化聯係起來,其原因至少部分是由于缺少一個研究快速靈活的動力學方法。 - 新華網  
  • 蛋白變性過程中間體的存在是蛋白變性及複性動力學研究中不可缺少的證據。以胰蛋白酶爲模型蛋白,用熒光光譜法系統地研究了在不同濃度變性則鹽酸胍存在時胰蛋白酶構象的變化,並與活性數據進行了對比。 思博網 - 思博網  
  • 鈣調素可以與很多不同的蛋白質結合,在結合鈣離子前後會發生構象變化,因此可以 在特定的反應中結合特定的蛋白質。 - 長庚大學物化生報告  
Gertrude Tsau
United States
Local time: 08:11
Native speaker of: Chinese
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  xxxMaryWong
12 hrs
  -> 謝謝!

Yes  jliu37
17 hrs
  -> 謝謝!

Yes  Hamish Young: Yes
19 hrs
  ->  謝謝!

Yes  nina yang
299 days
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2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5

Definition from 维基百科:

Example sentence(s):
  • 在本研究當中利用電化學與表面電漿共振技術來偵測人體血清白蛋白受鉻(VI)後導致構形的改變 - 人體血清白蛋白構形改變之電  
  • 在本研究中,我們認為突變型p53可能藉由bak蛋白質N端構形改變,而啟動粒線體細胞凋亡之機制,使得外送突變型p53於膀胱癌細胞株TCCSUP對抗癌藥物cisplatin產生高敏感性的現象。 - 探討外送突變型p53於膀胱癌細  
  • 在環境溫度變化對免疫球蛋白間鍵結的實驗結果中顯示分子間之交互作用力會隨著度增加而降低,此可歸因於溫度變化會引起分子構形改變造成生物分子間無法緊密皆合及溫度所造成的布朗運動碰撞分子間的鍵結,使鍵結強度降低。 - 利用原子力顯微術偵測單一生  
Yulin Chang
Local time: 22:11
Native speaker of: Native in ChineseChinese
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