18:54 Jun 17, 2005 |
English to French translations [PRO] Medical - Medical: Pharmaceuticals | |||||||
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| Selected response from: Andrés Martínez Spain Local time: 22:31 | ||||||
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4 | résistance médiée par (les tyrosine kinases) SRC |
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src-mediated resistance résistance médiée par (les tyrosine kinases) SRC Explanation: Src is the name of a family of tyrosine kinases, a kind of enzymes implied in cell proliferation, adhesion, migration, etc, key processes in tumoral growth. Src-family kinases : sites et documents francophones Synonyme(s) MeSH : Famille des kinases src ; Famille des tyrosine kinases src ; Kinases de la famille src ; Tyrosine kinases de la famille src . www.chu-rouen.fr/ssf/prod/srcfamilykinases.html http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d... Src family kinases (SFKs) have been implicated as important regulators of ligand-induced cellular responses including proliferation, survival, adhesion and migration. http://www.hxms.com/je/srcfam.html Src was the first proto-oncogenic protein described. Since then, many other tyrosine kinases have been identified and characterized. Src remains the ‘grandfather’ non-receptor tyrosine kinase and serves as a prototype for understanding the function and regulation of other tyrosine kinases (refs). The Src family is composed of nine members in vertebrates. http://webiologie.free.fr/cellules/membrane/recepteurs_enzym... Les tyrosine kinases Les tyrosine kinases constituent une famille d'enzymes très importante dans l'organisme eucaryote. Ces molécules ont en commun la propriété de phosphoryler un résidu tyrosine. Cette méthode est une méthode d'activation ou d'inactivation de certaines voies enzymatiques au sein de la cellule. La plupart de ces kinases sont des récepteurs membranaires. |
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