https://www.proz.com/kudoz/english-to-french/medical%3A-pharmaceuticals/2221048-peak-through-levels-.html
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Peak-through levels ...

French translation: concentrations au pic et au creux/nadir

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Peak-trough levels
French translation:concentrations au pic et au creux/nadir
Entered by: Dr Sue Levy (X)

12:35 Oct 27, 2007
English to French translations [PRO]
Medical - Medical: Pharmaceuticals / genetics
English term or phrase: Peak-through levels ...
Alors que l'expression est très usitée, je ne vois pas le sens exact de "Peak-through levels" dans :
With nilotinib plasma 'peak-trough levels of 3600-1700nM' at 400 mg twice daily dose, it is possible that longer treatment duration may result in further improvement in clinical responses in patients with less sensitive mutations.
Merci par avance
François Begon
France
Local time: 02:12
concentrations au pic et au creux/nadir
Explanation:
p.ex.
NEVIRAPINE- [ Translate this page ]Pic plasmatique (voisin de 2 microg/ml) 4 heures après une prise orale unique de ... A l'état d'équilibre, les concentrations au nadir sont voisines de 4,5 ...
www.biam2.org/www/Sub5159.html


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Note added at 1 hr (2007-10-27 14:26:47 GMT)
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autrement dit, les concentrations plasmatiques maximales (peak) et minimales (trough).
Selected response from:

Dr Sue Levy (X)
Local time: 02:12
Grading comment
Merci bcp
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1concentrations au pic et au creux/nadir
Dr Sue Levy (X)


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
peak-through levels ...
concentrations au pic et au creux/nadir


Explanation:
p.ex.
NEVIRAPINE- [ Translate this page ]Pic plasmatique (voisin de 2 microg/ml) 4 heures après une prise orale unique de ... A l'état d'équilibre, les concentrations au nadir sont voisines de 4,5 ...
www.biam2.org/www/Sub5159.html


--------------------------------------------------
Note added at 1 hr (2007-10-27 14:26:47 GMT)
--------------------------------------------------

autrement dit, les concentrations plasmatiques maximales (peak) et minimales (trough).

Dr Sue Levy (X)
Local time: 02:12
Does not meet criteria
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 108
Grading comment
Merci bcp

Peer comments on this answer (and responses from the answerer)
agree  Michael Lotz
3 hrs
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