This site uses cookies. Some of these cookies are essential to the operation of the site, while others help to improve your experience by providing insights into how the site is being used. For more information, please see the ProZ.com privacy policy.
Cookie settings
  1. KudoZ™ Top
  2. English to French
  3. Medical (general)

largely dispensable

French translation: en grande partie ne semble pas indispensable

14:31 Dec 24, 2016
English to French translations [PRO]
Medical - Medical (general) / infection au VIH
English term or phrase: largely dispensable
Around 1% of Northern Europeans lack functional CCR5 expression, due to a 32 base pair deletion in this gene. Individuals with the A32 allele of CCR5 are healthy, suggesting that CCR5 is largely dispensable. However, these individuals have very strong resistance to HIV infection
orgogozo
France
Local time: 09:13
French translation:en grande partie ne semble pas indispensable
Explanation:
PDF - thèse - Université Toulouse III - Paul Sabatier
thesesups.ups-tlse.fr/1088/1/Raymond_Stephanie.pdf
by S Raymond - ‎2010
18 Nov 2010 - 2.2.2.3. Régulation de l'expression des corécepteurs. 27. 2.3. .... Caractérisation de la résistance aux antagonistes de CCR5. 77 ...... La localisation de la molécule CD4 dans les rafts ne semble cependant pas indispensable au processus d'entrée du virus [Percherancier et al., 2003; Popik and Alce,. 2004].

--------------------------------------------------
Note added at 33 mins (2016-12-24 15:05:30 GMT)
--------------------------------------------------

Rôle et ciblage de l'intégrine α4β7 dans la physiopathologie des MICI ...
www.medecinesciences.org/en/.../medsci20153110p895.html - Translate this page
by A Girard - ‎2015 - ‎Cited by 1 - ‎Related articles
19 Oct 2015 - Les lymphocytes CD4+ Th17 semblent jouer un rôle majeur au niveau ..... (CD4 et CCR5), l'intégrine α4β7 ne semble pas indispensable à la ...
Selected response from:

liz askew
United Kingdom
Local time: 08:13
Grading comment
Merci à tous
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +2en grande partie ne semble pas indispensable
liz askew
4significativement superflu
Christine HOUDY
3non essentiel
memond


  

Answers


32 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
en grande partie ne semble pas indispensable


Explanation:
PDF - thèse - Université Toulouse III - Paul Sabatier
thesesups.ups-tlse.fr/1088/1/Raymond_Stephanie.pdf
by S Raymond - ‎2010
18 Nov 2010 - 2.2.2.3. Régulation de l'expression des corécepteurs. 27. 2.3. .... Caractérisation de la résistance aux antagonistes de CCR5. 77 ...... La localisation de la molécule CD4 dans les rafts ne semble cependant pas indispensable au processus d'entrée du virus [Percherancier et al., 2003; Popik and Alce,. 2004].

--------------------------------------------------
Note added at 33 mins (2016-12-24 15:05:30 GMT)
--------------------------------------------------

Rôle et ciblage de l'intégrine α4β7 dans la physiopathologie des MICI ...
www.medecinesciences.org/en/.../medsci20153110p895.html - Translate this page
by A Girard - ‎2015 - ‎Cited by 1 - ‎Related articles
19 Oct 2015 - Les lymphocytes CD4+ Th17 semblent jouer un rôle majeur au niveau ..... (CD4 et CCR5), l'intégrine α4β7 ne semble pas indispensable à la ...

liz askew
United Kingdom
Local time: 08:13
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 347
Grading comment
Merci à tous

Peer comments on this answer (and responses from the answerer)
agree  Drmanu49
31 mins
agree  PLR TRADUZIO (X)
53 mins
disagree  Germaine: Je ne vois pas le "seems for the most part" dispensable (si tant est qu'une chose puisse être à la fois superflue et indispensable)
2 hrs
agree  memond
4 hrs
Login to enter a peer comment (or grade)

1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
significativement superflu


Explanation:
IMO

Christine HOUDY
France
Local time: 09:13
Specializes in field
Native speaker of: French
PRO pts in category: 76

Peer comments on this answer (and responses from the answerer)
agree  Germaine: ou éminemment/grandement superflu
1 hr
  -> ou : tout à
disagree  memond: Attention la fonction d'un gene ne peut pas être 'significativement superflu'...
3 hrs
  -> ou "tout à fait superflu"
Login to enter a peer comment (or grade)

4 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
non essentiel


Explanation:
You have to be careful here; we are talking about the function of a gene. In this context, 'largely dispensable' means that the gene is not essential for the survival of the organism. So, the translation could be either what Liz proposed ...'pas indispensable...' or '...non essentiel...'

memond
Local time: 03:13
Specializes in field
Native speaker of: Native in FrenchFrench, Native in EnglishEnglish
PRO pts in category: 12
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

Return to KudoZ list

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.

See also:
ProZ.com term search
Search millions of term translations
Close search
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search