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English to German translations [PRO] Medical - Medical: Pharmaceuticals / alprostadil product characteristics
English term or phrase:in the mouse micronucleus assay
Alprostadil showed no evidence of mutagenicity in vitro in the Ames bacterial reverse mutation test, the unscheduled DNA synthesis assay in rat hepatocytes, or the Chinese hamster ovary forward gene mutation assay, and unscheduled DNA synthesis (UDS), nor was there evidence of mutagenicity in vivo **in the mouse micronucleus assay**, or rat micronucleus, sister chromatid exchange.