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21:44 Nov 8, 2013
This question was closed without grading. Reason: Answer found elsewhere
English to German translations [PRO] Medical - Medical (general)
English term or phrase:Integrated peripheral boost
Dies ist aus einer medizinischen Publikation:
***Integrated peripheral boost*** in preoperative radiotherapy for the
locally most advanced non-resectable rectal cancer patients
Few studies have explored the potential clinical advantages of dose escalation and integrated boosts for patients with non-resectable locally advanced rectal cancer.
Seven patients with locally very advanced rectal tumours (sacrum overgrowth or growth into pelvic side walls) were evaluated. Intensity modulated photon and pencil beam scanning proton plans with simultaneously integrated boosts (45 Gy to elective lymph nodes, 50 Gy to tumour and 62.5 Gy to boost area in 25 fractions) were compared. Adding boost to areas where rectal tumours infiltrate adjacent non-resectable organs is an attractive option which appears possible using both photon and proton irradiation. Proton plans reduced dose to organs at risk. ***Integrated peripheral boosts*** should be considered more frequently in these very advanced tumours.