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conformational change

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21:54 Feb 11, 2009
English to Japanese translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Genetics
English term or phrase: conformational change
Definition from Biochemical Society:
Large, medium or small adjustment to the molecular shape/dynamics of a protein that may follow a change in environment or the specific recognition of another molecule.

Example sentence(s):
  • These observations indicate that heparin, in addition to causing aggregation, also induces a conformational change in tau in which reactive groups are unmasked or move closer leading to the DSS cross-linking of 72- and 83-kDa species. jbc online
  • At low pH, the hemagglutinin (HA) of influenza virus undergoes an irreversible conformational change that potentiates its essential membrane fusion function. The Rockefeller University Press
  • To develop the antibody chip for detecting the Bax conformational change, we immobilized Bax monoclonal antibody 6A7, which recognizes only a conformationally changed Bax protein on a gold surface. Elsevier Inc.
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Summary of translations provided
4 +1コンフォメーション変化


Translations offered

78 days   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1

Definition from Wikipedia:

Example sentence(s):
  • 細胞膜の外側から情報伝達因子・神経ペプチドが受容体に結合すると、受容体の構造が変化し(コンホメーション変化)、細胞質側で受容体に結合しているGタンパク質の一連の分子間相互作用を誘起されます。 - 九州大学大学院 構造機能生  

Local time: 03:45
Native speaker of: Native in JapaneseJapanese

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Katsuhiko KAKUNO, Ph.D.
8 hrs
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