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English to Polish translations [PRO] Medical - Medical: Instruments
English term or phrase:suture clips
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Female Balb/c hairless mice with subcutaneously (s.c.) transplanted human bladder tumors T24 can be used
to determine the anti-tumor activity. On day 0, with the animals under peroral forene narcosis, approximately 25 mg of a solid tumor are placed under the skin on the animals’ left flank and the small incised wound is closed by means of suture clips. On day 6 after the transplantation, the mice are divided at random into groups of 6 animals and treatment commences. The treatment is carried out for 15 days with peroral, intravenous or intraperitoneal administration once daily (or less frequently) of a compound of formula (I) in DMSO/Tween80/sodium chloride solution in the various doses.
The tumors are measured twice a week with a slide gauge and the volume of the tumors is calculated.