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peg-milled

Polish translation: zmielony w młynie kołkowym

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:peg-milled
Polish translation:zmielony w młynie kołkowym
Entered by: Polangmar
Options:
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18:47 Dec 1, 2010
English to Polish translations [PRO]
Tech/Engineering - Medical: Pharmaceuticals
English term or phrase: peg-milled
Therefore, the tablets are manufactured via a direct compression process. To achieve adequate content uniformity in this low drug load formulation, the active ingredient is preferably pcg-milled. Preferably the particle size distribution of the peg-milled drug substance, as determined by laser diffractometry using a dry dispensing system, is characterized by particle fraction of 90 % (V/V) being smaller than 100 Pm, most preferably a particle fraction of 90 % (V/V) being smaller than 75 Pm in diameter.
Barbara Piela
Local time: 03:28
zmielona w młynie kołkowym
Explanation:
Czyli zmielona za pomocą, przy użyciu, przy zastosowaniu itp. młyna kołkowego.

...z uwagi na duże różnice w wielkości cząstek napotkanych w każdym przypadku zmniejszania wielkości poprzez rozdrabnianie lub zmniejszanie wielkości cząstek np. poprzez mielenie z użyciem różnego rodzaju obecnie dostępnych urządzeń do mielenia, np. młyna młotkowego, młyna kołkowego lub młyna strumieniowego...
http://pubserv.uprp.pl/PublicationServer/Temp/oh3jk7ocl43p00...

młyn kołkowy
http://tinyurl.com/25hf3ct

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Note added at 1 hr (2010-12-01 20:45:15 GMT)
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Przykłady urządzeń mielących obejmują młyn kołkowy, młyn młotkowy i młyn walcowy. Do innych odpowiednich urządzeń mielących należy na przykład młyn z perforowaną tarczą i młyn koloidowy, a samo mielenie można prowadzić...
http://pubserv.uprp.pl/PublicationServer/Temp/oh3jk7ocl43p00...
Selected response from:

Polangmar
Poland
Local time: 03:28
Grading comment
Dziękuję!
4 KudoZ points were awarded for this answer

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Summary of answers provided
4zmielona w młynie kołkowymPolangmar
Summary of reference entries provided
liz askew

Discussion entries: 1





  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
zmielona w młynie kołkowym


Explanation:
Czyli zmielona za pomocą, przy użyciu, przy zastosowaniu itp. młyna kołkowego.

...z uwagi na duże różnice w wielkości cząstek napotkanych w każdym przypadku zmniejszania wielkości poprzez rozdrabnianie lub zmniejszanie wielkości cząstek np. poprzez mielenie z użyciem różnego rodzaju obecnie dostępnych urządzeń do mielenia, np. młyna młotkowego, młyna kołkowego lub młyna strumieniowego...
http://pubserv.uprp.pl/PublicationServer/Temp/oh3jk7ocl43p00...

młyn kołkowy
http://tinyurl.com/25hf3ct

--------------------------------------------------
Note added at 1 hr (2010-12-01 20:45:15 GMT)
--------------------------------------------------

Przykłady urządzeń mielących obejmują młyn kołkowy, młyn młotkowy i młyn walcowy. Do innych odpowiednich urządzeń mielących należy na przykład młyn z perforowaną tarczą i młyn koloidowy, a samo mielenie można prowadzić...
http://pubserv.uprp.pl/PublicationServer/Temp/oh3jk7ocl43p00...

Polangmar
Poland
Local time: 03:28
Native speaker of: Native in PolishPolish
PRO pts in category: 443
Grading comment
Dziękuję!
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Reference comments


31 mins peer agreement (net): +1
Reference

Reference information:
I have tried looking for "peg-milled", and just keep coming across

polyethylene glycol

http://www.google.co.uk/search?q=the active ingredient is pr...

will see if I can find anything else

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Note added at 35 mins (2010-12-01 19:23:10 GMT)
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http://www.medilexicon.com/medicalabbreviations.php

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Note added at 42 mins (2010-12-01 19:29:47 GMT)
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http://webcache.googleusercontent.com/search?q=cache:L6jaFt6...


There are two basic prior art processes for grinding or milling agglomerates to reduce their particle size.

One of these processes uses an apparatus variously referred to as an annular chamber mill, grinding mill, agitator mill or peg mill. Development of this type of machine began with a hollow cylinder rotating on a horizontal axis and loaded with a certain amount of material to be ground and a certain quantity of grinding elements--most commonly small spherical steel balls but sometimes other hard substances such as walnut shells. The rotation of the cylinder causes the balls to tumble over and collide with each other in layers, grinding the material as the balls collide with each other. Typically, the loads were fed into the cylinder and ground for a period of six to sixty hours, depending on the size of the agglomerate and the desired size of the ground particles.

Next, vertical and horizontal agitator mills were developed by using a slow-running agitator to keep the ball charge moving. As with the horizontal tube mill, the vertical agitator mill operated periodically. During operation, a pump drew off the ground material at the bottom of the mill and pumped it back in at the top to make sure that it was uniformly processed.

More recently, particular attention has been paid to the shape and operation of the design of the agitators which keeps the ball charge activated. It was recognized that two out of the three factors which influence the grinding effect can be easily held constant. These are the size of the contact surface and the mass of the grinding balls. Therefore, the speed of the agitator arms, which sets the grinding elements in motion can be made to vary and thereby control operating parameters. Through development it was determined that the most efficient way of keeping the balls in motion is by the use of pegs which rotate through the ball charge. This led to the development of the annular chamber mill or peg mill of current design.

In current-style peg mills, the agitator is designed as a hollow shaft with a relatively large diameter. Pegs project outwardly from the shaft. The pegs are kept relatively short to limit the difference in speed between the hollow shaft and the extreme ends of the pegs. These pegs are arranged in rings on the hollow shaft, one above the other at relatively short intervals.

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Note added at 42 mins (2010-12-01 19:30:38 GMT)
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so, maybe the last reference is more useful?

Good luck!

liz askew
United Kingdom
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 11

Peer comments on this reference comment (and responses from the reference poster)
agree  Polangmar: Yes, if I had seen it earlier, it would have shortened my research. :-)
1 hr
  -> What a term to pin down. I had never heard of this before, mind you is that surprising?? Bye for now...
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Changes made by editors
Dec 10, 2010 - Changes made by Polangmar:
Created KOG entryKudoZ term » KOG term


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