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14:31 Nov 8, 2013
English to Polish translations [PRO] Medical - Medical: Pharmaceuticals / clinical studies
English term or phrase:carrier-linked
XXX is a novel prodrug that binds covalently to circulating albumin.
The drug is accumulated in tumors and doxorubicin is released in the tumor by cleaving the acid labile linker (EMCH) in the low pH tumor environment.
This carrier-linked prodrug has demonstrated enhanced antitumor activity with reduced toxicity in several murine models when compared with free doxorubicin.