Polish translation: Jak sie Pan/Pani miewa? Jak samopoczucie?
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Polish is much more formal than English, therefore, if you are meeting a person for the first time, you should stick to the formal way of addressing people: PAN/PANI. (PAN when addressing a male, PANI when addressing a female)
Unless this is a conversation with a youngster. In such instance, a direct way is advisable:
JAK SIĘ DZISIAJ MIEWASZ?
CO U CIEBIE DZISIAJ SŁYCHAĆ?