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down-regulation

Romanian translation: reducerea/diminuarea (răspunsului)

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09:52 Feb 6, 2009
English to Romanian translations [PRO]
Medical - Medical: Pharmaceuticals / medicamente antidepresive
English term or phrase: down-regulation
As in case of other anti-depressives, there was down-regulation of the responsiveness of cerebral norepinephrine receptors with long-term use of sertraline
Vertrad
Romania
Local time: 00:23
Romanian translation:reducerea/diminuarea (răspunsului)
Explanation:
down regulation / down regulation. [Eng[. down = fit jos; regulation = regCare.] Anglicism utilizat cu cel putin doua sensuri: 1) Diminuarea afinitatii unui recep�tor ca urmare a cresterii concentratiei sanguine a ligandului fiziologic In acest caz se poate utiliza ca sin. In romana ter-menul reglare joasa sau negativa. 2) Reducerea raspunsului unei celule la un anumit stimul, dupa prima expunere, ca urmare a reducerii numarului de receptori exprimati la nivelul suprafetei celulare.
http://www.medical.news20.ro/word/DOWN_REGULATION_.html

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Note added at 6 minute (2009-02-06 09:58:54 GMT)
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În alte contexte, l-am mai tradus ca reglare reductivă

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Note added at 7 minute (2009-02-06 09:59:43 GMT)
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sau reglare descendentă
www.imed.ro/rezidentiat2004/grile/pdf/farmacie/farmacie_par...
Selected response from:

Mihaela Petrican
Italy
Local time: 23:23
Grading comment
4 KudoZ points were awarded for this answer

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Summary of answers provided
4 +7reducerea/diminuarea (răspunsului)
Mihaela Petrican


  

Answers


5 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +7
reducerea/diminuarea (răspunsului)


Explanation:
down regulation / down regulation. [Eng[. down = fit jos; regulation = regCare.] Anglicism utilizat cu cel putin doua sensuri: 1) Diminuarea afinitatii unui recep�tor ca urmare a cresterii concentratiei sanguine a ligandului fiziologic In acest caz se poate utiliza ca sin. In romana ter-menul reglare joasa sau negativa. 2) Reducerea raspunsului unei celule la un anumit stimul, dupa prima expunere, ca urmare a reducerii numarului de receptori exprimati la nivelul suprafetei celulare.
http://www.medical.news20.ro/word/DOWN_REGULATION_.html

--------------------------------------------------
Note added at 6 minute (2009-02-06 09:58:54 GMT)
--------------------------------------------------

În alte contexte, l-am mai tradus ca reglare reductivă

--------------------------------------------------
Note added at 7 minute (2009-02-06 09:59:43 GMT)
--------------------------------------------------

sau reglare descendentă
www.imed.ro/rezidentiat2004/grile/pdf/farmacie/farmacie_par...

Mihaela Petrican
Italy
Local time: 23:23
Specializes in field
Native speaker of: Native in RomanianRomanian
PRO pts in category: 650

Peer comments on this answer (and responses from the answerer)
agree  lucca
1 min
  -> mulţumesc, Lucian!

agree  Irina-Maria Foray: :)
2 mins
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agree  RODICA CIOBANU
24 mins
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agree  cezara lucas
59 mins
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agree  Ciprian - Vasile Popescu
4 hrs
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agree  Tradeuro Language Services
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agree  Iosif JUHASZ
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