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|English to Russian translations [PRO]|
Medical - Biology (-tech,-chem,micro-)
|English term or phrase: pcy mice|
Помогите, пожалуйста, правильно перевести термин:
In **pcy mice**,37 an animal model of human nephronophthisis,
drug administration in diet showed a dose-dependent inhibition of the progression of PKD, as reflected by decreases in kidney weight, kidney cyst volume, kidney fibrosis volume, and mitotic index.
Благодарю за помощь!
|Russian translation:мыши линии pcy|
Полное название линии - DBA/2-pcy/pcy, а сокращенно ее называют просто pcy
Вот описание линии:
... we investigated the expression of MAPK in DBA/2-pcy/pcy (pcy) mice, a murine model of childhood PKD, juvenile nephronophthisis. Pcy mice have a missense mutation in NPHP3, the causal gene for human adolescent-type nephronophthisis (10). At an early stage, pcy mice are characterized by cysts that are derived predominantly from collecting ducts and urine concentration defect... Later in the course, all nephron segments become cystically dilated.
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