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frayed end

Russian translation: "Потрепанный конец" - см. пояснение

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20:23 Nov 22, 2013
English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: frayed end
Once the fusion probes are hybridized to their intended targets, a mixture of З'-end exonuclease and Klenow DNA polymerase (the EK mix) is added to the sample. As shown in step 2a, if the hybridization site is not at the very end of the template's З'-end, a """frayed end""" will form because the non-bacterial portion of the fusion probe will not bond with the template.
Спасибо!
dao2812
Russian translation:"Потрепанный конец" - см. пояснение
Explanation:
A frayed end refers to a region of a double stranded (or other multi-stranded) DNA molecule near the end with a significant proportion of non-complementary sequences; that is, a sequence where nucleotides on the adjacent strands do not match up correctly.
The term "frayed" is used because the incorrectly matched nucleotides tend to avoid bonding, thus appearing similar to the strands in a fraying piece of rope.
http://en.wikipedia.org/wiki/Sticky_and_blunt_ends
http://upload.wikimedia.org/wikipedia/commons/a/ac/Frayed-dn...


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Note added at 59 мин (2013-11-22 21:22:49 GMT)
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Это оно так и должно звучать, оно даже в википедии в кавычках, Вы его так и переводите: "Потрепанный" (в кавычках).
Возможны другие варианты: изношенный, истертый, потертый...
Любой здесь, в принципе, подойдет, потому что не состыкованным концам аминокислот нет такого научного названия...
Selected response from:

Andrey Svitanko
Poland
Local time: 10:36
Grading comment
Большое спасибо!
4 KudoZ points were awarded for this answer

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Summary of answers provided
4 +2"Потрепанный конец" - см. пояснение
Andrey Svitanko


  

Answers


42 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
"Потрепанный конец" - см. пояснение


Explanation:
A frayed end refers to a region of a double stranded (or other multi-stranded) DNA molecule near the end with a significant proportion of non-complementary sequences; that is, a sequence where nucleotides on the adjacent strands do not match up correctly.
The term "frayed" is used because the incorrectly matched nucleotides tend to avoid bonding, thus appearing similar to the strands in a fraying piece of rope.
http://en.wikipedia.org/wiki/Sticky_and_blunt_ends
http://upload.wikimedia.org/wikipedia/commons/a/ac/Frayed-dn...


--------------------------------------------------
Note added at 59 мин (2013-11-22 21:22:49 GMT)
--------------------------------------------------

Это оно так и должно звучать, оно даже в википедии в кавычках, Вы его так и переводите: "Потрепанный" (в кавычках).
Возможны другие варианты: изношенный, истертый, потертый...
Любой здесь, в принципе, подойдет, потому что не состыкованным концам аминокислот нет такого научного названия...

Andrey Svitanko
Poland
Local time: 10:36
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 531
Grading comment
Большое спасибо!
Notes to answerer
Asker: Спасибо! "Потрепанный" как-то ненаучно звучит.


Peer comments on this answer (and responses from the answerer)
agree  Maria Dynya
0 min
  -> Спасибо

agree  Natalie: "растрепанный"
18 mins
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