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17:55 Dec 6, 2004
This question was closed without grading. Reason: Errant question

English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: met
Таблица, озаглавленная Acute leukaemia: immunological markers and gene rearrangements.

В клетке, которая стоит на пересечении
линейки "Т-клеточный маркер CD2"
и колонки "Острые Т-лимфобластные лейкозы",

написано: + (- in met).

Судя по всему, это должно означать, что клетки при острых Т-лимфобластных лейкозах несут маркер CD2 (за исключением неких случаев -- met). Что за met? Метастазы, метамиелоциты и метионин, похоже, не годятся.

Local time: 11:00

Summary of answers provided
3metastatic cells do not express CD2recobra
3met - ген, рецептор фактора роста гепатоцитов
Ann Nosova
3met (1 мет = 58 Вт/м2; внесистемная единица метаболического теплообмена)
Svetlana Beloshapkina

Discussion entries: 11



59 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
met (1 мет = 58 Вт/м2; внесистемная единица метаболического теплообмена)

Found this - will it help? Seems that it could be what you're looking for.

    Reference: http://multitran.ru/c/m.exe?t=3069118_2_1
Svetlana Beloshapkina
United States
Local time: 01:00
Native speaker of: Russian

Peer comments on this answer (and responses from the answerer)
neutral  Alya: если бы все проблемы решались путем простого заглядывания в словарь... Как ВЫ себе представляете данное значение в данном контексте, а???
6 hrs
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15 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
met - ген, рецептор фактора роста гепатоцитов

Из всего, что я просмотрела, это ближе всего к истине. Хотя мне не удалось разгадать, почему его так назвали.
MET ( HGFR) met proto-oncogene (hepatocyte growth factor receptor)Other names c-met http://www.infobiogen.fr/services/chromcancer/Genes/METID131...
The MET receptor (1408 amino acids) is initially synthesized as a partially glycosylated 170 kDa single chain precursor. Following further glycosylation, it is cleaved at a basic amino acid site into an a- and b-chain. http://www.bloodjournal.org/cgi/content/full/90/11/4450
Hepatocyte growth factor-scatter factor (HGF-SF ) mediates mito-, moto-, and morphogenic effects through the MET receptor, a membrane bound tyrosine kinase. HGF-SF/MET signaling is mitogenic for a large number of epithelial and endothelial cells and activates organ regeneration. HGF-SF transcripts have been detected in various myeloid cell lines.
c-Met is a tyrosine kinase receptor for hepatocyte growth factor and suggested to be involved in oncogenesis ormetastatic phenotypes in many malignancies. Adult T-cell leukemia (ATL) is a neoplasia characterized by massive invasion of the leukemic HGF, also known as scatter factor, was identified as a chemoattractant for a variety of cells.
The second pair consists of a scatter factor, hepatocyte growth factor (HGF), and its receptor Met, a tyrosine kinase from the MET/RON/SEA oncogene family. Although HGF and Met are important during normal embryonic development, they have also been associated with malignancy when mutated in certain ways.

In particular, CD2 was expressed on 96% of the abnormal cells from the MET-1 patient examined ex vivo and on 99% of the spleen cells of the MET-1–bearing NOD /SCID mice
....the limited expression of CD2 that is restricted to mature T cells and T-leukemic cells including MET-1 leukemic cells provides the scientific rationale for its use in antibody-mediated immunotherapy.

Ann Nosova
United States
Local time: 04:00
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 71
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18 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
metastatic cells do not express CD2

metastatic cells
Я не нашел подтверждения, что metastatic cells или metastatic tumor cells сокращают как met. Но косвенные данные попадаются: названия линий клеток,выделенных из опухолей, этот ген met, возможно тоже отсюда.
Если это так, то в met клетках не должно быть экспресcии CD2.

Several antigens associated with normal cell types (Lineage
markers: CD2, CD3, CD10, CD16, CD18, CD31, CD64, and
CD140b) were found not to be expressed by the cancer cells
based on analyses of tumors that had been passaged multiple
times in mice.

Находятся еще ссылки, где вроде об этом есть, они они за деньги

Local time: 11:00
Native speaker of: Native in RussianRussian
PRO pts in category: 16
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