linkage drag

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08:25 Jun 5, 2018
English to Russian translations [PRO]
Law/Patents - Genetics / Гены, ассоциированные с повышенной урожайностью
English term or phrase: linkage drag
A marker that demonstrates linkage with a locus affecting a desired phenotypic trait provides a useful tool for the selection of the trait in a plant population. This is particularly true where the phenotype is hard to assay or occurs at a late stage in plant development. Since DNA marker assays are less laborious and take up less physical space than field phenotyping, much larger populations can be assayed, increasing the chances of finding a recombinant with the target segment from the donor line moved to the recipient line. The closer the linkage, the more useful the marker, as recombination is less likely to occur between the marker and the gene causing or imparting the trait. Having flanking markers decreases the chances that false positive selection will occur. The ideal situation is to have a marker in the gene itself, so that recombination cannot occur between the marker and the gene. Such a marker is called a “perfect marker.”
When a gene is introgressed by MAS, it is not only the gene that is introduced but also the flanking regions. Gepts, Crop Sci 42:1780 (2002). This is referred to as "linkage drag." In the case where the donor plant is highly unrelated to the recipient plant, these flanking regions carry additional genes that can code for agronomically undesirable traits. This "linkage drag" can also result in reduced yield or other negative agronomic characteristics even after multiple cycles of backcrossing into the elite maize line. This is also sometimes referred to as "yield drag."

Встречал такой вариант перевода как "сопротивление, обусловленное сцеплением генов".
Local time: 01:28

Summary of answers provided
3сцепленный груз
Igor Andreev



30 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
сцепленный груз

предложил бы еще как вариант чуть более длинно
перенос сцепленного с целевым признаком (или с целевым геном) балластного генетического материала

"сопротивление" - ерунда )

Эффективность решения такой важной селекционной задачи, как повышение генетического разнообразия сельскохозяйственных культур, напрямую связана с возможностью управления процессом генетической рекомбинации. Главным источником новых генов для улучшения сортов могли бы стать неадаптированные формы и родственные дикие виды, однако широкое их использование часто наталкивается на ряд негативных явлений. Одно из них - проблема "сцепленного груза" (linkage drag) , которая заключается в подавлении рекомбинации в районах, сцепленных с селекционно-ценным геном, что приводит к попаданию в создаваемую элитную форму помимо нужного ряда генов нежелательных генов из дикого вида.


Igor Andreev
Local time: 01:28
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 72
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