canonical pathway associated with the dataset

Russian translation: см.

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22:22 Dec 3, 2016
English to Russian translations [PRO]
Medical - Mathematics & Statistics /
English term or phrase: canonical pathway associated with the dataset
Blood samples collected from patients in the mITT population provided a unique opportunity to assess in a post hoc analysis the effect of treatment on genome-wide gene expression.Differentially expressed gene lists for IFN-b versus placebo treatment were generated for Days 4 (88 genes) and 7 (94 genes) by selecting probes that were significant at P less than 0.05 and had a fold change of greater than 1.25 following analysis of covariance, including Day 1 as a covariate.Analysis of these data using Ingenuity Pathway Analysis software suggested enhanced type I IFN signaling on both days. After correction for multiple testing using a Benjamini-Hochberg procedure, IFN signaling was the only canonical pathway that was significantly associated with the dataset.
Dannie_R
Ukraine
Local time: 00:39
Russian translation:см.
Explanation:
"IFN сигнальный путь являлся единственным каноническим (классическим) путем, который был достоверно связан с данным набором данных"
IFN-b - так понимаю интерферон бета, с которым связан некий сигнальный путь. Вероятно, в силу каких-то причин (факторов), таких путей м.б. несколько и они могут различаться какими-то нюансами. Но один из этих путей - основной, т.е. канонический (классический), все остальные - побочные.
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Marlin31
Russian Federation
Local time: 00:39
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Marlin31


  

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1 day 10 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
см.


Explanation:
"IFN сигнальный путь являлся единственным каноническим (классическим) путем, который был достоверно связан с данным набором данных"
IFN-b - так понимаю интерферон бета, с которым связан некий сигнальный путь. Вероятно, в силу каких-то причин (факторов), таких путей м.б. несколько и они могут различаться какими-то нюансами. Но один из этих путей - основной, т.е. канонический (классический), все остальные - побочные.


Marlin31
Russian Federation
Local time: 00:39
Native speaker of: Native in RussianRussian
PRO pts in category: 12
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спасибо
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