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Lateral Membrane Domain

Russian translation: латеральные домены мембраны

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Lateral Membrane Domains
Russian translation:латеральные домены мембраны
Entered by: Pavel Venediktov
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14:00 Jun 26, 2007
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: Lateral Membrane Domain
Lateral Membrane Domains Organize and Regulate Components of Signal Transduction Pathways.
Utilized fluorescence digital imaging microscopy to analyze formation of lateral membrane domains induced by signal transduction peptides and proteins.
Olena Bilonoh
Ukraine
Local time: 05:51
латеральные домены мембраны
Explanation:
Речь идет о латеральной гетерогенности мембран:
Membrane rafts
The organization of surface receptors and signaling components in the membrane and interactions with the cytoskeleton contribute to the balance of positive and negative factors that regulates TCR signaling. The first data to suggest that the fluid mosaic model had to be modified to incorporate lateral membrane domains were based on fluorescent dyes that reported differing degrees of order in the hydrophobic core of biological membranes (21). The concept of membrane domains was given biochemical substance by the observation that one class of domains enriched in cholesterol and sphingolipids is not fully soluble in nonionic detergents and can be isolated as a low-density fraction on density gradients.
и примерно тоже самое на русском :
В последние годы жидкостно-мозаичная модель тоже подверглась модификации, и этот процесс будет продолжаться. В частности, теперь стало ясно, что не все мембранные белки свободно диффундируют в жидком липидном бислое. Имеются данные о существовании латеральных доменов в самой мембране.
http://festival.1september.ru/2005_2006/index.php?numb_artic...

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Note added at 35 мин (2007-06-26 14:36:38 GMT)
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Первую ссылку забыл вставить:
www.jci.org/cgi/reprint/109/2/155.pdf
Selected response from:

Pavel Venediktov
Russian Federation
Local time: 05:51
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer

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Summary of answers provided
4латеральные домены мембраны
Pavel Venediktov


  

Answers


33 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
lateral membrane domain
латеральные домены мембраны


Explanation:
Речь идет о латеральной гетерогенности мембран:
Membrane rafts
The organization of surface receptors and signaling components in the membrane and interactions with the cytoskeleton contribute to the balance of positive and negative factors that regulates TCR signaling. The first data to suggest that the fluid mosaic model had to be modified to incorporate lateral membrane domains were based on fluorescent dyes that reported differing degrees of order in the hydrophobic core of biological membranes (21). The concept of membrane domains was given biochemical substance by the observation that one class of domains enriched in cholesterol and sphingolipids is not fully soluble in nonionic detergents and can be isolated as a low-density fraction on density gradients.
и примерно тоже самое на русском :
В последние годы жидкостно-мозаичная модель тоже подверглась модификации, и этот процесс будет продолжаться. В частности, теперь стало ясно, что не все мембранные белки свободно диффундируют в жидком липидном бислое. Имеются данные о существовании латеральных доменов в самой мембране.
http://festival.1september.ru/2005_2006/index.php?numb_artic...

--------------------------------------------------
Note added at 35 мин (2007-06-26 14:36:38 GMT)
--------------------------------------------------

Первую ссылку забыл вставить:
www.jci.org/cgi/reprint/109/2/155.pdf

Pavel Venediktov
Russian Federation
Local time: 05:51
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 1149
Grading comment
Спасибо!
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Changes made by editors
Jun 27, 2007 - Changes made by Pavel Venediktov:
Created KOG entryKudoZ term » KOG term


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