with about two-thirds compliance

Russian translation: на фоне соблюдения/при соблюдении режима лечения двумя третями пациентов

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15:57 Dec 2, 2016
English to Russian translations [PRO]
Medical - Medical: Cardiology / Efficacy and safety of LDL reduction in patients with chronic kidney disease
English term or phrase: with about two-thirds compliance
Allocation to simvastatin plus ezetimibe yielded an average LDL cholesterol difference of 0·85 mmol/L (SE 0·02; *****with about two-thirds compliance*****) during a median follow-up of 4·9 years and produced a 17% proportional reduction in major atherosclerotic events (526 [11·3%] simvastatin plus ezetimibe vs 619 [13·4%] placebo; rate ratio [RR] 0·83, 95% CI 0·74—0·94; log-rank p=0·0021).
Margarita Vidkovskaia
Russian Federation
Local time: 16:55
Russian translation:на фоне соблюдения/при соблюдении режима лечения двумя третями пациентов
Explanation:
Маргарита, я в статистике не спец, но что-то нутром чую, что здесь все же хотели сказать о том, что вот эти average LDL cholesterol difference of 0·85 mmol/L были получены на фоне комплаентности 2/3 пациентов.

И там де смотрите дальше по статье:

On average, however, only two-thirds of the patients allocated simvastatin plus ezetimibe were taking an LDL-cholesterol-lowering regimen and so, with full compliance, the LDL cholesterol reduction would typically have been about 1·3 (ie, 0·85×3/2) mmol/L.

As a result, the intention-to-treat comparisons assess the effects of around two-thirds of participants actually taking LDL-cholesterol-lowering treatment daily, which yielded an average LDL cholesterol difference of 0·85 mmol/L (SE 0·02; table 2).
Selected response from:

Evgeni Kushch
Ukraine
Local time: 16:55
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
3на фоне соблюдения/при соблюдении режима лечения двумя третями пациентов
Evgeni Kushch


  

Answers


3 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
на фоне соблюдения/при соблюдении режима лечения двумя третями пациентов


Explanation:
Маргарита, я в статистике не спец, но что-то нутром чую, что здесь все же хотели сказать о том, что вот эти average LDL cholesterol difference of 0·85 mmol/L были получены на фоне комплаентности 2/3 пациентов.

И там де смотрите дальше по статье:

On average, however, only two-thirds of the patients allocated simvastatin plus ezetimibe were taking an LDL-cholesterol-lowering regimen and so, with full compliance, the LDL cholesterol reduction would typically have been about 1·3 (ie, 0·85×3/2) mmol/L.

As a result, the intention-to-treat comparisons assess the effects of around two-thirds of participants actually taking LDL-cholesterol-lowering treatment daily, which yielded an average LDL cholesterol difference of 0·85 mmol/L (SE 0·02; table 2).

Evgeni Kushch
Ukraine
Local time: 16:55
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 95
Grading comment
Спасибо!
Notes to answerer
Asker: Евгений, большое спасибо! Я тоже так поняла (с приверженностью терапии 2/3 пациентов), но ваша формулировка мне больше понравилась. https://www.nephrology.edu.au/downloads/presentations/DNT%202011/05%20Rob%20Walker%20v1.pdf LDL‐C reduction of 0.83 mmol/l (32 mg/dL) with 2/3 compliance, equivalent to 1.3 mmol/l (50 mg/dL) with full compliance.

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